{"id":"W2407316653","doi":"10.1111/gbb.12302","title":"Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test","year":2016,"lang":"en","type":"article","venue":"Genes Brain & Behavior","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health","keywords":"Biology; Genetics; Expression quantitative trait loci; Quantitative trait locus; Candidate gene; Mechanosensation; Locus (genetics); Gene; Genotype; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002947663,0.0002542499,0.0002648851,0.0002912695,0.0002660478,0.000220908,0.0003731809,0.00007275653,0.00006489956],"category_scores_gemma":[0.0004376445,0.0001551802,0.0001007154,0.0006947551,0.0001903174,0.0001272177,0.0001074056,0.00007760362,0.00002447812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004482883,"about_ca_system_score_gemma":0.00004095029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001245948,"about_ca_topic_score_gemma":0.0002519299,"domain_scores_codex":[0.9972789,0.0007599635,0.0003845069,0.0007465971,0.0004355503,0.0003945083],"domain_scores_gemma":[0.9981157,0.001218861,0.0001405353,0.0003643293,0.00005434484,0.0001062786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007820568,0.000104456,0.07205026,0.000006564979,0.00001131519,0.00007773182,0.0001818005,0.0001773401,0.9208935,0.00003743684,0.00006425497,0.006387504],"study_design_scores_gemma":[0.0004085615,0.00007692327,0.4295144,0.00001019909,0.0004535843,0.00003024187,0.0002295753,0.0004571635,0.5684406,0.00003455959,0.0001156369,0.0002285877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968083,0.0007305758,0.0006205575,0.0006268367,0.0002735735,0.0007586395,0.0001185004,0.00005303029,0.0000100223],"genre_scores_gemma":[0.9982635,0.0004200457,0.00006114451,0.0004645216,0.00007201551,0.0004174879,0.000006108899,0.00002172303,0.0002734453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3574642,"threshold_uncertainty_score":0.6328065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07078858613528732,"score_gpt":0.3292978577553058,"score_spread":0.2585092716200185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}