{"id":"W2407316653","doi":"10.1111/gbb.12302","title":"Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test","year":2016,"lang":"en","type":"article","venue":"Genes Brain & Behavior","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health","keywords":"Biology; Genetics; Expression quantitative trait loci; Quantitative trait locus; Candidate gene; Mechanosensation; Locus (genetics); Gene; Genotype; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002477945,0.0005226257,0.0003609856,0.0005876657,0.0002347666,0.0003423396,0.0003510905,0.000347849,0.001714371],"category_scores_gemma":[0.0002858927,0.0002078482,0.0002797225,0.0002334595,0.0005190112,0.0001948999,0.0004399253,0.0004138375,0.0001471022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005420232,"about_ca_system_score_gemma":0.0004493182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001315895,"about_ca_topic_score_gemma":0.001768122,"domain_scores_codex":[0.9997527,0.00003648518,0.00001770318,0.00008820883,0.0000618558,0.00004303825],"domain_scores_gemma":[0.9998693,0.00004116778,0.00004778799,0.00001085571,0.000009228094,0.00002162406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001149627,0.00002653147,0.0007866283,0.00002546288,0.000009096523,0.00005372646,0.000007947244,0.0001366393,0.9969235,0.00023724,0.00001852082,0.001659639],"study_design_scores_gemma":[0.00013689,0.001245667,0.1074823,0.00002678102,0.0001510514,0.0008099544,0.00008353977,0.01046067,0.876268,0.0008494845,0.002429904,0.0000557744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890608,0.0004657695,0.008971502,0.00009837456,0.00001059125,0.00005452472,0.0004025997,0.000116104,0.0008197672],"genre_scores_gemma":[0.9901391,0.0004663587,0.007526609,0.00008267959,0.000005359071,0.0001268182,0.0004643931,0.00001972162,0.001168998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001714371,"threshold_uncertainty_score":0.005735159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07078858613528732,"score_gpt":0.3292978577553058,"score_spread":0.2585092716200185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}