{"id":"W2407762868","doi":"10.1097/mot.0000000000000217","title":"Clinical applications of next-generation sequencing in histocompatibility and transplantation","year":2015,"lang":"en","type":"review","venue":"Current Opinion in Organ Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Transplantation; Computational biology; DNA sequencing; Sanger sequencing; Single cell sequencing; Bioinformatics; Biology; Medicine; Exome sequencing; DNA; Mutation; Genetics; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001608865,0.001004178,0.001620959,0.002508138,0.0002408012,0.001015301,0.0008712507,0.001472339,0.00390694],"category_scores_gemma":[0.002187487,0.0002566404,0.0006513923,0.00246361,0.0006730189,0.001395503,0.0008478464,0.0017757,0.002237887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007027164,"about_ca_system_score_gemma":0.001481452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009763118,"about_ca_topic_score_gemma":0.001339854,"domain_scores_codex":[0.999581,0.0001043945,0.00006424548,0.00007375488,0.0001463405,0.00003027324],"domain_scores_gemma":[0.9986687,0.0007554362,0.0001695232,0.00003017474,0.0002963871,0.00007982516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004428731,0.00003018892,0.0002426172,0.01818263,0.0001148376,0.000174793,0.00004588319,0.0004257368,0.001291148,0.002408145,0.02519738,0.9518423],"study_design_scores_gemma":[0.00001370305,0.000071095,0.00130896,0.007800864,0.0001699325,0.001674861,0.00007871548,0.0002011439,0.0007270504,0.002788095,0.9851324,0.00003327291],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006869801,0.9983851,0.0002544798,0.0004196922,0.0002965735,0.000004912868,0.00001353406,0.000008694653,0.0005484245],"genre_scores_gemma":[0.0005576128,0.998193,0.0003538794,0.0002991968,0.0003004039,0.000006709475,0.00002873786,0.000002510768,0.000258064],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00390694,"threshold_uncertainty_score":0.01306999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3752317946493904,"score_gpt":0.4785266249841027,"score_spread":0.1032948303347123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}