{"id":"W2407949236","doi":"10.1016/j.cellimm.2016.05.005","title":"Protein tyrosine phosphatase 1B (PTP1B) is dispensable for IgE-mediated cutaneous reaction in vivo","year":2016,"lang":"en","type":"article","venue":"Cellular Immunology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Beatrice Hunter Cancer Research Institute; McGill University; Dalhousie University","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Degranulation; Tyrosine phosphorylation; Protein tyrosine phosphatase; Immunoglobulin E; Mast cell; Phosphorylation; Biology; Cell biology; Tyrosine; Dephosphorylation; Syk; LYN; In vivo; STAT protein; Signal transduction; Phosphatase; Immunology; Tyrosine kinase; Antibody; Receptor; Biochemistry; Proto-oncogene tyrosine-protein kinase Src; STAT3","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004211172,0.0006152326,0.0004942933,0.0004918597,0.0002618863,0.0006553284,0.0004593926,0.00057036,0.002354586],"category_scores_gemma":[0.0004323646,0.0004373277,0.0003134918,0.0001915023,0.0006132541,0.0006062918,0.0004041086,0.00188595,0.0008642351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004120829,"about_ca_system_score_gemma":0.0003152782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000455809,"about_ca_topic_score_gemma":0.0005121952,"domain_scores_codex":[0.9994672,0.0001158016,0.00003678394,0.0001097781,0.0001242299,0.0001461571],"domain_scores_gemma":[0.999292,0.0001799509,0.000165663,0.00009933164,0.00003785108,0.0002250625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004610524,0.00004389216,0.0001237276,0.00003050579,0.000004279808,0.00007787193,0.000006903793,0.00002604143,0.9984795,0.0001038312,0.00003642704,0.0006059454],"study_design_scores_gemma":[0.000163783,0.0008788277,0.007611472,0.00001705738,0.00005962818,0.001338014,0.0000659699,0.001962056,0.9857971,0.0002868415,0.001808438,0.00001073383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923238,0.0034274,0.002284111,0.0001808837,0.00006745307,0.0000220662,0.0003032473,0.00009465333,0.001296462],"genre_scores_gemma":[0.9962878,0.0006723569,0.0007547716,0.00004279079,0.00002665526,0.00002484904,0.0003719091,0.00004494407,0.00177404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002354586,"threshold_uncertainty_score":0.007876873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008292760508718099,"score_gpt":0.2024355282130171,"score_spread":0.194142767704299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}