{"id":"W2408318972","doi":"10.1158/2326-6074.cricimteatiaacr15-b074","title":"Abstract B074: Tumor-reactive CD4+ T cells in metastatic gastrointestinal cancer refractory to chemotherapy","year":2016,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"CIITA; Cancer research; CD8; Cancer; Major histocompatibility complex; Immunotherapy; T cell; Tumor-infiltrating lymphocytes; MHC class I; Medicine; Biology; Immune system; Immunology; MHC class II; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002252616,0.0002927562,0.0004528737,0.0002952525,0.0003104104,0.0002688158,0.0001704081,0.0004359941,0.002641524],"category_scores_gemma":[0.0004257622,0.0001371034,0.0001680162,0.0001730098,0.000205889,0.0001716244,0.0001292487,0.0002920214,0.0004452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002771312,"about_ca_system_score_gemma":0.0001472142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004326321,"about_ca_topic_score_gemma":0.0004385478,"domain_scores_codex":[0.9998955,0.00002613275,0.00001036428,0.00002312268,0.0000160162,0.00002892568],"domain_scores_gemma":[0.9998233,0.00005408981,0.00002716276,0.00001074819,0.00001524732,0.00006942851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01539642,0.001311524,0.5535121,0.0003861922,0.0001384289,0.01859432,0.000599229,0.000849935,0.3524371,0.0002026511,0.002231944,0.05434014],"study_design_scores_gemma":[0.00117615,0.02666762,0.863766,0.00007487978,0.000281172,0.05339637,0.0003762394,0.003047779,0.04461858,0.0001753205,0.006393929,0.00002589674],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988723,0.0003187113,0.00009302941,0.00004019967,0.000004631432,0.00001936539,0.00004795365,0.0000101413,0.0005935935],"genre_scores_gemma":[0.9990364,0.0001059896,0.0001799512,0.00007964441,0.00002505575,0.00002138477,0.0002034104,0.0000040838,0.0003440819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002641524,"threshold_uncertainty_score":0.008836806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0541671101081283,"score_gpt":0.3716468242514702,"score_spread":0.3174797141433419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}