{"id":"W2408323684","doi":"10.1093/infdis/jiw156","title":"Schistosome Soluble Egg Antigen Decreases<i>Mycobacterium tuberculosis</i>–Specific CD4<sup>+</sup>T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation","year":2016,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Global Health Research","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Tuberculosis; Mycobacterium tuberculosis; Immunology; Biology; Antigen; T cell; Peripheral blood mononuclear cell; Macrophage; Interleukin 4; Cytokine; Microbiology; Molecular biology; Immune system; Medicine; In vitro; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009034059,0.000258221,0.0001847201,0.0001125828,0.00005844361,0.000168705,0.00006791705,0.0002111841,0.002338388],"category_scores_gemma":[0.000118659,0.0001102841,0.0001583166,0.00005393769,0.0001535407,0.0001087471,0.0001133114,0.0004320331,0.0003367547],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001035275,"about_ca_system_score_gemma":0.00009728652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002264672,"about_ca_topic_score_gemma":0.0004339147,"domain_scores_codex":[0.9999056,0.00001962171,0.00001148395,0.00001362052,0.00001861573,0.00003116925],"domain_scores_gemma":[0.99992,0.00001228236,0.00002685038,0.000007748272,0.00001090802,0.0000221868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002365459,0.00003452058,0.0006165524,0.0000315488,0.000003798403,0.00002755995,0.000006084402,0.00001906977,0.9980609,0.00001233483,0.00003134945,0.0009196587],"study_design_scores_gemma":[0.00003299497,0.001596529,0.0507155,0.000009805729,0.0000241617,0.0004415037,0.00005025958,0.0007159146,0.9452828,0.00003917787,0.001088274,0.000003100393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984556,0.0003607919,0.0004290079,0.00005781913,0.00001567281,0.0000111639,0.0001142652,0.00003693767,0.0005187485],"genre_scores_gemma":[0.9978207,0.0002067566,0.000426905,0.00005063851,0.000009219776,0.00001554574,0.0002295686,0.000007707291,0.001232854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002338388,"threshold_uncertainty_score":0.007822633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005356418984591516,"score_gpt":0.2179919501697411,"score_spread":0.2126355311851496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}