{"id":"W2408323684","doi":"10.1093/infdis/jiw156","title":"Schistosome Soluble Egg Antigen Decreases<i>Mycobacterium tuberculosis</i>–Specific CD4<sup>+</sup>T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation","year":2016,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Global Health Research","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Tuberculosis; Mycobacterium tuberculosis; Immunology; Biology; Antigen; T cell; Peripheral blood mononuclear cell; Macrophage; Interleukin 4; Cytokine; Microbiology; Molecular biology; Immune system; Medicine; In vitro; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002369262,0.0002768619,0.0004692334,0.0002211285,0.0003331716,0.00003703178,0.0002254853,0.0001272639,0.001012385],"category_scores_gemma":[0.00009030677,0.0001471171,0.000270946,0.0001956036,0.0002627247,0.0004765533,0.00004164867,0.0002931541,0.0004032545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001488971,"about_ca_system_score_gemma":0.0001418272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000681614,"about_ca_topic_score_gemma":0.00001723981,"domain_scores_codex":[0.998324,0.0004524632,0.000598278,0.0001835419,0.00011944,0.0003222727],"domain_scores_gemma":[0.9977573,0.0006694631,0.0007595737,0.0003442323,0.0003745593,0.00009486739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004895432,0.0008223354,0.06374458,0.00005405341,0.000714394,0.00001875429,0.0001986257,0.0002019709,0.922859,0.00004793002,0.005824064,0.0006188906],"study_design_scores_gemma":[0.02058376,0.009570629,0.4894741,0.001555487,0.003687286,0.004264053,0.0009681168,0.00002816052,0.4268417,0.0004710073,0.04127465,0.001281007],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896193,0.006949249,0.001019669,0.0001606329,0.001319201,0.0002785008,0.0001573188,0.00004923442,0.0004468594],"genre_scores_gemma":[0.9977224,0.001377236,0.00001109079,0.00008724393,0.0002361724,0.00001087826,0.00004220875,0.00003215746,0.0004806003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4960172,"threshold_uncertainty_score":0.9999008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005356418984591516,"score_gpt":0.2179919501697411,"score_spread":0.2126355311851496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}