{"id":"W2408608019","doi":"10.1038/srep21563","title":"Modulation of oligodendrocyte differentiation and maturation by combined biochemical and mechanical cues","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European Regional Development Fund; College of Pharmacy and Nutrition, University of Saskatchewan; Fundação para a Ciência e a Tecnologia; Ministerio de Economía y Competitividad","keywords":"Oligodendrocyte; Myelin; Myelin basic protein; Cell biology; Extracellular matrix; Fibronectin; Cellular differentiation; Progenitor cell; Proteolipid protein 1; Biology; Chemistry; Neuroscience; Biochemistry; Stem cell; Central nervous system; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001278494,0.0003209607,0.0001452717,0.0001076298,0.00008163718,0.0002088767,0.0001217542,0.000178151,0.0006897043],"category_scores_gemma":[0.0001440888,0.00009548828,0.0001187939,0.00008874856,0.0001363485,0.0001499819,0.0002558339,0.0002072848,0.000142965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008351245,"about_ca_system_score_gemma":0.0001236367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002223595,"about_ca_topic_score_gemma":0.000689625,"domain_scores_codex":[0.9998525,0.00002587388,0.00001342675,0.00001767586,0.0000580709,0.00003239866],"domain_scores_gemma":[0.9999218,0.00001429821,0.00002552115,0.000006567043,0.00001255111,0.0000193138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002189462,0.000006029387,0.0001033274,0.00002347698,0.000001571299,0.00002072403,0.000004644305,0.00002852943,0.9989243,0.00001558275,0.000004159358,0.0008456284],"study_design_scores_gemma":[0.000004881108,0.0004060965,0.008591419,0.000009641396,0.00001217186,0.0001886214,0.00003838172,0.0005851079,0.9886472,0.00003404952,0.001476104,0.00000641234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996163,0.001324401,0.001668369,0.00002278182,0.00001039154,0.00001106692,0.00004453111,0.00001189533,0.0007434674],"genre_scores_gemma":[0.996075,0.001000707,0.00203245,0.00001589404,0.000007138241,0.00001944124,0.00007318375,0.000005272643,0.0007708882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006897043,"threshold_uncertainty_score":0.002307355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005865146364617861,"score_gpt":0.2197578032094883,"score_spread":0.2138926568448704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}