{"id":"W2408608019","doi":"10.1038/srep21563","title":"Modulation of oligodendrocyte differentiation and maturation by combined biochemical and mechanical cues","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European Regional Development Fund; College of Pharmacy and Nutrition, University of Saskatchewan; Fundação para a Ciência e a Tecnologia; Ministerio de Economía y Competitividad","keywords":"Oligodendrocyte; Myelin; Myelin basic protein; Cell biology; Extracellular matrix; Fibronectin; Cellular differentiation; Progenitor cell; Proteolipid protein 1; Biology; Chemistry; Neuroscience; Biochemistry; Stem cell; Central nervous system; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001644117,0.00006260728,0.0000713488,0.00003249492,0.00006161359,0.00003679413,0.00002443996,0.00006999053,0.00001371502],"category_scores_gemma":[0.00006736641,0.00004651949,0.00002555555,0.00003927048,0.00005639965,0.00001050585,0.00004032245,0.00001957284,4.943931e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006114212,"about_ca_system_score_gemma":0.00001165313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003907352,"about_ca_topic_score_gemma":0.000003646157,"domain_scores_codex":[0.9992895,0.00001679678,0.0002019393,0.0003083833,0.000107667,0.00007567518],"domain_scores_gemma":[0.9995443,0.000005731205,0.0001289017,0.0002004603,0.00007691251,0.00004371292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001913052,0.000022878,0.0002280147,0.000005835,0.000008402881,4.97882e-7,0.000008055848,1.570508e-7,0.996588,0.0001760314,0.001998219,0.00094479],"study_design_scores_gemma":[0.0001383855,0.000054449,0.000807135,0.00001432374,0.000009189385,0.00003173279,0.000007201957,0.0004205524,0.9946597,0.001797313,0.001996757,0.00006322751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888096,0.000163715,0.01022616,0.00009506717,0.0005760823,0.00008815128,0.000005359806,0.000005549012,0.00003031709],"genre_scores_gemma":[0.9990027,0.00005626367,0.0001563938,0.000005894683,0.00002309982,0.000004840181,0.0001660742,0.000005554237,0.0005791673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01019311,"threshold_uncertainty_score":0.189701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005865146364617861,"score_gpt":0.2197578032094883,"score_spread":0.2138926568448704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}