{"id":"W2409086625","doi":"10.1101/pdb.top087262","title":"In Vitro Investigation of Synaptic Plasticity","year":2016,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre; Montreal General Hospital","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research","keywords":"Neocortex; Neuroscience; Hippocampal formation; Long-term potentiation; Excitatory postsynaptic potential; Pyramidal cell; Synaptic plasticity; Plasticity; Slice preparation; Spike-timing-dependent plasticity; Computer science; Electrophysiology; Biology; Physics; Inhibitory postsynaptic potential","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003475866,0.0007362938,0.0005295264,0.0003972696,0.0004465373,0.0004221771,0.001058989,0.000529058,0.001901262],"category_scores_gemma":[0.0002590819,0.0003440948,0.0005554697,0.0003344192,0.0004455451,0.0005396928,0.0007176319,0.001558405,0.001225616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004819671,"about_ca_system_score_gemma":0.0002676782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006050573,"about_ca_topic_score_gemma":0.001437694,"domain_scores_codex":[0.9995505,0.00008319091,0.00006113311,0.0001149422,0.0001305715,0.00005955681],"domain_scores_gemma":[0.9996393,0.0001427668,0.00004733941,0.0001000011,0.00003736939,0.00003319166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001410828,0.00002441909,0.00006304643,0.00009507098,0.000009704446,0.00009058284,0.00002163226,0.0001147705,0.9980797,0.0005445314,0.00008127518,0.0008610669],"study_design_scores_gemma":[0.00001115848,0.0002204981,0.000913199,0.00002311775,0.00004175447,0.0003818788,0.00002064718,0.001239177,0.9894511,0.0004538555,0.00723602,0.000007570205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.5189409,0.02462615,0.3966169,0.001170247,0.001486104,0.0009732706,0.006942109,0.001523636,0.04772075],"genre_scores_gemma":[0.827142,0.02065849,0.1348026,0.0006725119,0.0003645674,0.001459722,0.003735335,0.0002578101,0.01090694],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.001901262,"threshold_uncertainty_score":0.006360352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0709999115892941,"score_gpt":0.3460459838318736,"score_spread":0.2750460722425795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}