{"id":"W2409100747","doi":"10.2147/jir.s104790","title":"Toll-like receptor cascade and gene polymorphism in host–pathogen interaction in Lyme disease","year":2016,"lang":"en","type":"review","venue":"Journal of Inflammation Research","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Public Health Agency of Canada","funders":"Public Health Agency; Public Health Agency of Canada","keywords":"Borrelia burgdorferi; Biology; Immunology; Innate immune system; Lyme disease; Toll-like receptor; TLR2; Pathogen; Proinflammatory cytokine; Pattern recognition receptor; Disease; Immune system; Genetics; Inflammation; Medicine; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002514752,0.0003336252,0.001121444,0.002793448,0.0001223937,0.00007375404,0.0003837589,0.0005324584,0.0009162539],"category_scores_gemma":[0.001740055,0.0002480635,0.0003082944,0.0005809322,0.0002231333,0.0004585083,0.0001949188,0.001583626,0.0006596933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009552321,"about_ca_system_score_gemma":0.001162029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008134244,"about_ca_topic_score_gemma":0.0001433195,"domain_scores_codex":[0.9947749,0.002517926,0.001552427,0.0003628738,0.0002526777,0.0005392272],"domain_scores_gemma":[0.9971587,0.001055677,0.0008794271,0.0003440001,0.0004120908,0.0001500859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001045135,0.0003749042,0.002128418,0.003699055,0.0005781801,0.000469804,0.0005046061,0.000004394487,0.03422802,0.0001451629,0.004674116,0.9521482],"study_design_scores_gemma":[0.001355849,0.0001529376,0.002751369,0.01097144,0.0001040394,0.0006167855,0.00004692318,6.892436e-7,0.0002503035,0.00007893585,0.983377,0.0002937507],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05890662,0.9389817,0.0000129216,0.0003565338,0.0008480187,0.0007099952,0.00008941095,0.00001398546,0.00008077578],"genre_scores_gemma":[0.00447717,0.9939572,0.000018963,0.00001333458,0.0003742431,0.00008509362,0.0001097935,0.00004685415,0.0009174051],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9787028,"threshold_uncertainty_score":0.9999971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0670224232634659,"score_gpt":0.385183505591207,"score_spread":0.318161082327741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}