{"id":"W2409158050","doi":"10.1385/1-59259-115-9:283","title":"Analyzing the Contributions of Chromatin Structure in Nuclear Hormone Receptor Activated Transcription In Vivo","year":2003,"lang":"en","type":"review","venue":"Humana Press eBooks","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Medical Research Council","keywords":"Chromatin; Pioneer factor; ChIA-PET; Transcription coregulator; Nucleosome; Histone-modifying enzymes; Transcription factor; Promoter; Chromatin remodeling; Nuclear receptor; Biology; Cell biology; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005024208,0.0002465258,0.0001820877,0.000336695,0.0002343127,0.0004709874,0.0003780567,0.0003478936,0.001108043],"category_scores_gemma":[0.0002978687,0.0003045491,0.0002646198,0.0001742636,0.000404727,0.0003105572,0.0002535902,0.0005792047,0.0004110207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005216032,"about_ca_system_score_gemma":0.0001870902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008121127,"about_ca_topic_score_gemma":0.001420697,"domain_scores_codex":[0.9996548,0.00007634197,0.00002046038,0.0001057862,0.00009447937,0.00004807835],"domain_scores_gemma":[0.9996715,0.0001265563,0.00006533322,0.0000444447,0.00003965572,0.00005252938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007715083,0.00001485408,0.0004139247,0.00002194851,0.000003516336,0.00001494686,0.00002132482,0.00004952952,0.9981948,0.0001719624,0.00001050701,0.001005586],"study_design_scores_gemma":[0.00003271722,0.000429707,0.01917299,0.0000173128,0.00002478521,0.0002938012,0.00005730115,0.001826956,0.9747238,0.0002727557,0.003135619,0.00001229395],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9557351,0.01435501,0.02463288,0.0002136214,0.0001265848,0.00009217978,0.0006914453,0.0001587424,0.003994334],"genre_scores_gemma":[0.9853162,0.002423759,0.007793461,0.0001180245,0.00005778812,0.00006820517,0.001337815,0.00004492695,0.002839806],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001108043,"threshold_uncertainty_score":0.003784478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02107096574514558,"score_gpt":0.2840112842614329,"score_spread":0.2629403185162873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}