{"id":"W2409633283","doi":"10.2174/1389557515666160509125829","title":"Review of Cytotoxic CA4 Analogues that Do Not Target Microtubules: Implications for CA4 Development","year":2016,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Windsor","funders":"","keywords":"Cytotoxic T cell; Microtubule; Chemistry; Cell biology; Biology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004441586,0.0008605206,0.001154648,0.001838585,0.0002856051,0.0006973177,0.0009694415,0.0008137624,0.00443649],"category_scores_gemma":[0.0005667301,0.0003587392,0.0005096963,0.001788164,0.0003470812,0.001082096,0.0004957549,0.001650049,0.002383112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000575306,"about_ca_system_score_gemma":0.0008005671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006463721,"about_ca_topic_score_gemma":0.001399099,"domain_scores_codex":[0.9998527,0.00002377124,0.00002458335,0.00002803031,0.00005468597,0.00001629318],"domain_scores_gemma":[0.9997815,0.00008267874,0.00004097557,0.000008330379,0.00006032913,0.00002610569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001287083,0.0001099599,0.0001163773,0.02908881,0.0001193289,0.0003110399,0.00007689771,0.0007821355,0.006869651,0.004576395,0.05367922,0.9041414],"study_design_scores_gemma":[0.00001993729,0.0001242398,0.0003691721,0.001561733,0.00009227187,0.0008186736,0.00002576106,0.00009327455,0.001136084,0.0008633354,0.9948798,0.00001569781],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002458504,0.9973379,0.0002802384,0.000276451,0.0003930233,0.00001100556,0.00004043937,0.00001744392,0.00139757],"genre_scores_gemma":[0.001102271,0.997039,0.0003641131,0.0002836396,0.0001790854,0.00001408575,0.0000693624,0.000003482783,0.0009449704],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00443649,"threshold_uncertainty_score":0.01484156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04955457320813372,"score_gpt":0.349008924551681,"score_spread":0.2994543513435473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}