{"id":"W2409810875","doi":"10.1038/srep27485","title":"CdGAP/ARHGAP31, a Cdc42/Rac1 GTPase regulator, is critical for vascular development and VEGF-mediated angiogenesis","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University Health Centre; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"Institute of Cancer Research; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Institut Du Cancer de Montréal; Université de Montréal","keywords":"Angiogenesis; CDC42; RAC1; Cell biology; Sprouting angiogenesis; Biology; Protein kinase B; Cancer research; Vascular endothelial growth factor A; RHOA; Vascular endothelial growth factor; Vascular endothelial growth factor B; Phosphorylation; Signal transduction; Neovascularization; VEGF receptors","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007069905,0.0003768002,0.0001551467,0.0004506042,0.0003856821,0.0003262771,0.0001823588,0.0003462323,0.0008239434],"category_scores_gemma":[0.0001218933,0.0001231316,0.0001156418,0.0002252138,0.0002823489,0.000117186,0.0003811157,0.0003231276,0.0003862744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003048184,"about_ca_system_score_gemma":0.0002616669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009270881,"about_ca_topic_score_gemma":0.0008299098,"domain_scores_codex":[0.9998971,0.00001270598,0.000005290029,0.0000266591,0.00003877822,0.00001948289],"domain_scores_gemma":[0.9998896,0.00001015497,0.00004738139,0.000005451388,0.000009965569,0.00003733571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001014781,0.00001345684,0.001355521,0.00005763336,0.000006421563,0.0007669468,0.00002464874,0.000166478,0.9902458,0.0007042626,0.0002604535,0.006296924],"study_design_scores_gemma":[0.00002885741,0.0002062932,0.06049747,0.00002928794,0.00003652737,0.01234183,0.0001040179,0.002851518,0.8850377,0.0006148237,0.03822985,0.00002179216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815177,0.007587908,0.005255073,0.0003473939,0.000051965,0.00002567126,0.0008917429,0.0003090944,0.004013374],"genre_scores_gemma":[0.9941182,0.001723693,0.001709707,0.00003684328,0.00001077097,0.00001509532,0.0006278197,0.0000214413,0.001736345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009270881,"threshold_uncertainty_score":0.002756357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0142524870952681,"score_gpt":0.2626635952193971,"score_spread":0.248411108124129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}