{"id":"W2410100735","doi":"10.1038/srep27862","title":"Effects of LDL Receptor Modulation on Lymphatic Function","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Fondation Institut de Cardiologie de Montréal; Institut de Cardiologie de Montréal; Banting Research Foundation","keywords":"Lymphatic system; Lymphatic vessel; LDL receptor; PCSK9; Endothelial dysfunction; Lymphatic Endothelium; Immune system; Medicine; Lesion; Macrophage; Endothelium; Cholesterol; Pathology; Biology; Internal medicine; Immunology; Lipoprotein; Cancer; In vitro; Metastasis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000438067,0.00008853976,0.0001865706,0.0001563329,0.00006735674,0.0000206617,0.00002606004,0.0000435279,0.0002025577],"category_scores_gemma":[0.0007101972,0.00005126028,0.00009389215,0.0002248155,0.00009571407,0.0001030297,0.00001180189,0.000003941448,0.0001241019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009038562,"about_ca_system_score_gemma":0.0001524927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005572431,"about_ca_topic_score_gemma":3.465934e-7,"domain_scores_codex":[0.9985428,0.00003975783,0.0003687233,0.0003697134,0.0005426378,0.0001363686],"domain_scores_gemma":[0.9988341,0.0001157354,0.0002573324,0.0005091333,0.0001606732,0.0001230231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002173072,0.000464876,0.04477732,0.0007020374,0.00006149436,0.0001207413,0.0001236432,0.00000817586,0.8796397,0.0002460097,0.02598527,0.04765345],"study_design_scores_gemma":[0.002911847,0.0006205507,0.2802232,0.002897725,0.0003231566,0.0001842453,0.00005497926,0.0001390766,0.6953177,0.006685817,0.01037354,0.0002681091],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889754,0.000143151,0.001267205,0.0001162266,0.006934107,0.0005061532,8.626117e-7,0.00006072126,0.001996174],"genre_scores_gemma":[0.9914942,0.000001837443,0.00006169295,0.00003532614,0.0001163888,0.00002575824,0.00001451321,0.00001010603,0.008240154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2354459,"threshold_uncertainty_score":0.2217865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00916670707835287,"score_gpt":0.2363044236809104,"score_spread":0.2271377166025575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}