{"id":"W2410248495","doi":"10.1387/ijdb.11460999","title":"Formation of retinal pigment epithelium in vitro by transdifferentiation of neural retina cells","year":2001,"lang":"en","type":"article","venue":"The International Journal of Developmental Biology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Transdifferentiation; Biology; Cell biology; Retina; Retinal pigment epithelium; Neural cell adhesion molecule; Retinal; Embryonic stem cell; Muller glia; Epithelium; Cell type; Cell adhesion; Cell; Stem cell; Genetics; Neuroscience; Progenitor cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004542434,0.000509772,0.0005540845,0.0003362295,0.0001724076,0.000372935,0.0005695069,0.0003820573,0.0009621924],"category_scores_gemma":[0.0002968456,0.0003080994,0.0006515284,0.0002439528,0.0001871871,0.0001981615,0.0005744512,0.000886145,0.001014882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002724121,"about_ca_system_score_gemma":0.00022531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001614901,"about_ca_topic_score_gemma":0.002870527,"domain_scores_codex":[0.9993622,0.00007198669,0.0001210837,0.0001417892,0.000237836,0.00006526339],"domain_scores_gemma":[0.9995193,0.0001082921,0.00005554881,0.000144675,0.00009235617,0.00007985628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006300816,0.0000178932,0.0001711073,0.00008864839,0.000007635233,0.00007048831,0.00005445544,0.0001610227,0.9975738,0.00007382534,0.00003897905,0.00167914],"study_design_scores_gemma":[0.0000208722,0.0003544841,0.003432167,0.00003260768,0.00004014327,0.0003369017,0.00003784488,0.001820405,0.9857907,0.00004493629,0.008080233,0.000008597229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9500028,0.008147122,0.02765044,0.000114113,0.0003103203,0.0003824971,0.00189712,0.0003019206,0.01119366],"genre_scores_gemma":[0.9362878,0.005258382,0.04196026,0.0001754085,0.00004556792,0.0003313741,0.004426526,0.0001190215,0.01139574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001614901,"threshold_uncertainty_score":0.003218889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007146637652741832,"score_gpt":0.2318024001573314,"score_spread":0.2246557625045895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}