{"id":"W2410289784","doi":"10.1186/s40795-016-0074-6","title":"A randomized controlled trial of the effects of a prudent diet on cardiovascular risk factors, gene expression, and DNA methylation - the Diet and Genetic Intervention (DIGEST) Pilot study","year":2016,"lang":"en","type":"article","venue":"BMC Nutrition","topic":"Nutrition, Genetics, and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; St. Michael's Hospital; Population Health Research Institute; University of Toronto; McMaster University","funders":"","keywords":"Medicine; Randomized controlled trial; Saturated fat; Clinical nutrition; Single-nucleotide polymorphism; Environmental health; Internal medicine; Cholesterol; Genotype; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006763802,0.0001699274,0.0005372438,0.00004932482,0.0001030764,0.00001644901,0.0001044896,0.00006703394,0.000001746738],"category_scores_gemma":[0.001040441,0.00008347719,0.0004428848,0.00004833093,0.0001761051,0.000005942271,0.00007360585,0.00004058393,1.272506e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001000743,"about_ca_system_score_gemma":0.00001985727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003227079,"about_ca_topic_score_gemma":0.00001593265,"domain_scores_codex":[0.9970965,0.001761188,0.0004606694,0.0002974386,0.000273585,0.0001106389],"domain_scores_gemma":[0.9986941,0.000366987,0.0003388551,0.0004271517,0.0001226922,0.00005019686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6687065,0.002044483,0.003616244,0.0002018086,0.0004380518,3.118826e-7,0.00007924209,0.000006949234,0.3246689,0.000005595101,0.00003072873,0.0002011813],"study_design_scores_gemma":[0.7190606,0.007293513,0.02540397,0.0001903482,0.0008065886,6.996283e-7,0.0000755049,0.000006738585,0.2465948,0.000438544,0.0000249116,0.000103852],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838494,0.007999224,0.001515622,0.00001954068,0.0002221476,0.006344893,0.00003927764,0.000005591163,0.000004287818],"genre_scores_gemma":[0.9952829,0.003594034,0.00006634496,0.000005200932,0.0001717143,0.0008329071,0.00001946299,0.00001398359,0.00001342492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07807413,"threshold_uncertainty_score":0.3404101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009838603439045197,"score_gpt":0.2421412766945528,"score_spread":0.2323026732555076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}