{"id":"W2410440539","doi":"10.1016/j.molcel.2016.05.025","title":"Visualizing Clonal Evolution in Cancer","year":2016,"lang":"en","type":"review","venue":"Molecular Cell","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre","funders":"","keywords":"Biology; Somatic evolution in cancer; Evolutionary biology; Computational biology; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001171065,0.00117007,0.001298704,0.002835899,0.0003247701,0.001802383,0.00139044,0.001906887,0.002545364],"category_scores_gemma":[0.001319716,0.0006043055,0.0003907646,0.002026879,0.001508977,0.002709821,0.001381031,0.002593579,0.00166631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001351881,"about_ca_system_score_gemma":0.0009507907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001423715,"about_ca_topic_score_gemma":0.002516246,"domain_scores_codex":[0.9996985,0.00005856334,0.00002318177,0.00005842182,0.0001257616,0.00003559018],"domain_scores_gemma":[0.9994676,0.0002638982,0.00005999398,0.00002730094,0.0001227441,0.00005854814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008163726,0.00003646868,0.0002356877,0.007542755,0.00006426913,0.0002039851,0.00007848936,0.0007256974,0.008794174,0.01591888,0.04532365,0.9209942],"study_design_scores_gemma":[0.00001923962,0.00003388226,0.0004659618,0.001524032,0.00007293674,0.001191695,0.0000433989,0.0004706589,0.005022789,0.008261194,0.9828623,0.00003182559],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001306534,0.99674,0.001106377,0.000398194,0.0003630891,0.000004252065,0.00001790283,0.00002810772,0.001211384],"genre_scores_gemma":[0.002220566,0.9931113,0.001347181,0.0004995384,0.0006371377,0.00001185747,0.00005369421,0.00001066192,0.002108084],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002835899,"threshold_uncertainty_score":0.0098086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01701544680317151,"score_gpt":0.3208559995543682,"score_spread":0.3038405527511966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}