{"id":"W2410440539","doi":"10.1016/j.molcel.2016.05.025","title":"Visualizing Clonal Evolution in Cancer","year":2016,"lang":"en","type":"review","venue":"Molecular Cell","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre","funders":"","keywords":"Biology; Somatic evolution in cancer; Evolutionary biology; Computational biology; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001232395,0.0003355466,0.0005483345,0.0001199266,0.00002918502,0.00002443904,0.0002656846,0.0004119212,0.00004190764],"category_scores_gemma":[0.0000365592,0.0002949121,0.0003490693,0.0001310657,0.00004037781,0.000001399289,0.0001939624,0.0001512735,0.00005974437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002034191,"about_ca_system_score_gemma":0.0005805506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008100726,"about_ca_topic_score_gemma":0.00006450857,"domain_scores_codex":[0.9984955,0.00008896863,0.0003778849,0.0005564537,0.0001303472,0.0003508482],"domain_scores_gemma":[0.9992585,0.00001939323,0.000184666,0.0004103272,0.00004063717,0.00008652337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000217297,0.0001606185,0.0000525968,0.004735122,0.0001373181,0.0001131192,0.00001224071,0.00003710182,0.01521165,0.0006051311,0.003114631,0.9757987],"study_design_scores_gemma":[0.000266933,0.00005718456,0.000003346724,0.001834874,0.00009499522,0.000005772354,0.000001906636,0.000002009202,0.00143079,0.00004930009,0.9958572,0.0003956203],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001808005,0.9953766,0.001533621,0.00001336984,0.000352155,0.0003519072,0.0001433867,0.00000676621,0.002041361],"genre_scores_gemma":[0.0005673296,0.9978502,0.0001072051,0.0001032366,0.0003591023,0.0001659592,0.0002339663,0.00008428231,0.0005286783],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9927427,"threshold_uncertainty_score":0.9999503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01701544680317151,"score_gpt":0.3208559995543682,"score_spread":0.3038405527511966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}