{"id":"W2410472750","doi":"10.1136/jmedgenet-2015-103577.30","title":"MG-141 A further report of paediatric cancer and cleidocranial dysplasia raises the possibility of a causative association of weak effect","year":2015,"lang":"en","type":"article","venue":"Clinical Genetics","topic":"Bone health and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cleidocranial Dysplasia; Medicine; Cancer; Dysplasia; Missense mutation; Relative risk; Oncology; Internal medicine; Mutation; Genetics; Confidence interval; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001593569,0.00008932754,0.0005134117,0.00002372782,0.00001547533,0.000001433965,0.0000395704,0.0001536791,0.00001015476],"category_scores_gemma":[0.002853319,0.0000545928,0.0001044394,0.000140806,0.0001682337,0.00001034567,0.00003507489,0.0001440913,0.000001284834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005225528,"about_ca_system_score_gemma":0.0004595195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004124677,"about_ca_topic_score_gemma":0.0001830703,"domain_scores_codex":[0.9983042,0.0002559335,0.0008365207,0.0001765261,0.000297797,0.0001289673],"domain_scores_gemma":[0.997409,0.001078163,0.0007272154,0.0002701386,0.000360234,0.0001552888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006945111,0.0002859948,0.9880998,0.0001243424,0.0001601374,0.000007246902,0.0003292854,0.000001673321,0.00004983848,0.000002089288,0.0004334553,0.009811671],"study_design_scores_gemma":[0.004011025,0.001945546,0.9921023,0.0000401961,0.0005461713,0.000008866302,0.00004568718,0.00006468152,0.0007168369,0.0001295526,0.0003502649,0.00003888739],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964086,0.001564832,0.000006150291,0.0008838396,0.0002471269,0.00056238,0.00003680247,0.000005242881,0.0002850715],"genre_scores_gemma":[0.9987198,0.000548883,0.0002551177,0.00008146373,0.0001080676,0.00001375634,0.000005962458,0.000008653068,0.0002583415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009772784,"threshold_uncertainty_score":0.3415896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05587833688481181,"score_gpt":0.415246666850148,"score_spread":0.3593683299653362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}