{"id":"W2410740411","doi":"","title":"Aging issues in drug disposition and efficacy.","year":2007,"lang":"en","type":"article","venue":"PubMed","topic":"Pharmaceutical Practices and Patient Outcomes","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Medicine; Intensive care medicine; Drug; Pharmacotherapy; Polypharmacy; Population; Geriatrics; Population ageing; Elderly people; Cohort; Gerontology; Pharmacology; Internal medicine; Psychiatry; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009404257,0.000465429,0.001009853,0.001098048,0.0005405296,0.002559955,0.0005684112,0.001992543,0.008178823],"category_scores_gemma":[0.03135725,0.0002299812,0.0006994329,0.001308251,0.001474998,0.003555608,0.00103028,0.002617969,0.002479632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001765097,"about_ca_system_score_gemma":0.003177804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002280063,"about_ca_topic_score_gemma":0.003429179,"domain_scores_codex":[0.9954984,0.001982072,0.0006972824,0.000290974,0.001391875,0.0001393739],"domain_scores_gemma":[0.9786673,0.01131688,0.004013769,0.0009320271,0.004044293,0.001025719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003948625,0.0001119051,0.01088191,0.002251063,0.00020876,0.0004597711,0.0003599598,0.0003022599,0.0004188759,0.03236605,0.1015774,0.8506671],"study_design_scores_gemma":[0.0001320027,0.001389649,0.0411415,0.004600336,0.0005012511,0.006022916,0.0006628491,0.001150154,0.0009817644,0.05133578,0.8920015,0.00008030435],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005888441,0.8696433,0.002698071,0.08345948,0.004343567,0.00003782311,0.000267918,0.0000950201,0.03356646],"genre_scores_gemma":[0.1375082,0.7793772,0.005138613,0.03964123,0.02145392,0.0001065091,0.0003158501,0.00005142705,0.01640706],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.009404257,"threshold_uncertainty_score":0.04973507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07170348311326752,"score_gpt":0.3776302733262838,"score_spread":0.3059267902130163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}