{"id":"W2410812161","doi":"10.1210/me.2016-1039","title":"Phoenixin Activates Immortalized GnRH and Kisspeptin Neurons Through the Novel Receptor GPR173","year":2016,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto General Hospital; University Health Network","funders":"University of Toronto; Canada Research Chairs; King's College London","keywords":"Kisspeptin; Biology; Gonadotropin-releasing hormone; Internal medicine; Endocrinology; Messenger RNA; CREB; Transcription factor; Hypothalamus; Gene; Luteinizing hormone; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002299689,0.0002203003,0.0002431438,0.0002033936,0.0001998791,0.0003254033,0.0002215667,0.0001900897,0.002478249],"category_scores_gemma":[0.0001086048,0.0002209261,0.0004553331,0.0002380603,0.0002079112,0.0002144389,0.0003068489,0.0006462975,0.0007947243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002274052,"about_ca_system_score_gemma":0.0002444198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005453276,"about_ca_topic_score_gemma":0.0006925684,"domain_scores_codex":[0.9997256,0.00002717259,0.00003956191,0.00005244827,0.00007790222,0.00007723939],"domain_scores_gemma":[0.9999248,0.00001400094,0.00001591551,0.00001586371,0.000007910345,0.00002146804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002841978,0.00006438298,0.0002657849,0.00004559497,0.000008745355,0.0001417991,0.00004554756,0.00005048362,0.9974153,0.000215003,0.0001213799,0.001341793],"study_design_scores_gemma":[0.00009609756,0.0004233084,0.005844405,0.000007430629,0.00002833647,0.0005228729,0.00008139004,0.0009119365,0.9809279,0.0001103118,0.01103935,0.000006625939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886649,0.001088621,0.003910866,0.0001554047,0.0001150171,0.0001212707,0.001923945,0.0001005884,0.003919326],"genre_scores_gemma":[0.9809982,0.001531021,0.003708133,0.0001200233,0.00003098101,0.0002371937,0.004534618,0.00005965008,0.008780056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002478249,"threshold_uncertainty_score":0.008290529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01742884947040629,"score_gpt":0.2664320635268148,"score_spread":0.2490032140564085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}