{"id":"W2411037073","doi":"10.1142/s0129065716500441","title":"Extracellular Potassium and Seizures: Excitation, Inhibition and the Role of Ih","year":2016,"lang":"en","type":"article","venue":"International Journal of Neural Systems","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Ictal; Depolarization; Extracellular; Neocortex; Hyperpolarization (physics); In vivo; Chemistry; Population; Cortical spreading depression; Epilepsy; Membrane potential; Potassium; Neuroscience; Biophysics; Internal medicine; Stereochemistry; Medicine; Biology; Biochemistry; Nuclear magnetic resonance spectroscopy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002459299,0.0000499758,0.00007744685,0.00004804917,0.00002272615,0.00002302848,0.00005478754,0.00004105825,0.000004278536],"category_scores_gemma":[0.000088638,0.00002671325,0.00004055903,0.0000180378,0.0000831963,0.00001525294,0.00002136718,0.00002856394,4.3125e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007841913,"about_ca_system_score_gemma":0.00001250602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008578171,"about_ca_topic_score_gemma":0.00000118231,"domain_scores_codex":[0.9993798,0.00007324892,0.0002612312,0.0000645571,0.0001791445,0.00004203915],"domain_scores_gemma":[0.9992724,0.00003564212,0.0002759218,0.00004226666,0.0003460597,0.00002770432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006400564,0.0000207032,0.002422555,0.000009301438,0.00009482923,0.00000514567,0.0001555006,0.0001380391,0.9837031,0.005332938,0.0004694395,0.007008358],"study_design_scores_gemma":[0.04067409,0.002793061,0.07080869,0.001433544,0.0002655864,0.01485637,0.007178906,0.02394607,0.4887811,0.01838049,0.3297553,0.00112679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907611,0.00326733,0.003599409,0.001393607,0.0008147227,0.00006734761,0.00000745136,0.000001522863,0.00008750482],"genre_scores_gemma":[0.9987902,0.0002186505,0.00001613268,0.0000275646,0.0006078194,0.000001897277,0.000004039128,0.00000432623,0.0003293904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4949221,"threshold_uncertainty_score":0.1089335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006774644163211336,"score_gpt":0.2225553165002824,"score_spread":0.2157806723370711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}