{"id":"W2411331668","doi":"10.1016/j.cbpa.2016.05.021","title":"Applications of CRISPR-Cas in its natural habitat","year":2016,"lang":"en","type":"review","venue":"Current Opinion in Chemical Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Fonds de recherche du Québec – Nature et technologies; Novalait; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"CRISPR; Natural (archaeology); Biology; Computational biology; Genetics; Gene; Paleontology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001169761,0.0002799923,0.0007022236,0.0001618929,0.000007759571,0.000003042676,0.0003543597,0.0004583246,0.00001196453],"category_scores_gemma":[0.0001196517,0.0002205366,0.0002224706,0.0002010032,0.00009073348,0.000001518832,0.0002099463,0.0002999525,0.00001804642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004275703,"about_ca_system_score_gemma":0.00008966465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001059001,"about_ca_topic_score_gemma":0.000001571428,"domain_scores_codex":[0.9984515,0.0000631123,0.000635976,0.000505102,0.00005372032,0.0002905759],"domain_scores_gemma":[0.9993494,0.00007340655,0.0001514813,0.0003273648,0.00004305239,0.00005535868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000006898259,0.00007265742,0.00009693838,0.004967717,0.00002056467,8.755217e-8,0.000005135583,3.636314e-7,0.008193062,0.0001985447,0.000371094,0.9860669],"study_design_scores_gemma":[0.0002517765,0.00002727264,0.000007755061,0.002564804,0.00001131566,0.000007339272,0.000001652614,0.000002553597,0.006184176,0.00006648277,0.9906232,0.0002516609],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005594663,0.996484,0.001610997,0.00001658881,0.001189085,0.0004761967,0.0001119916,0.000006716235,0.0000484959],"genre_scores_gemma":[0.002056073,0.9960161,0.00009660489,0.000002898894,0.0005237582,0.000328714,0.0009401397,0.00002376803,0.00001193054],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9902521,"threshold_uncertainty_score":0.8993223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03831153786019007,"score_gpt":0.4464723381115263,"score_spread":0.4081608002513362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}