{"id":"W2411351210","doi":"10.1007/s40120-016-0045-5","title":"Neuropsychiatric Adverse Reactions to Mefloquine: a Systematic Comparison of Prescribing and Patient Safety Guidance in the US, UK, Ireland, Australia, New Zealand, and Canada","year":2016,"lang":"en","type":"article","venue":"Neurology and Therapy","topic":"Pharmacovigilance and Adverse Drug Reactions","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; MedDRA; Drug reaction; Mefloquine; Family medicine; Drug; Adverse drug reaction; Patient safety; Psychiatry; Pharmacovigilance; Malaria; Pathology; Health care; Chloroquine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02663318,0.0002808411,0.001618703,0.007245014,0.0004617414,0.001087288,0.0006226262,0.0006990503,0.0005090703],"category_scores_gemma":[0.08736072,0.0003430325,0.002086194,0.01010168,0.0009025206,0.0007804154,0.001000462,0.0004573089,0.00005679222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003903982,"about_ca_system_score_gemma":0.01069036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.07126763,"about_ca_topic_score_gemma":0.1609919,"domain_scores_codex":[0.9587205,0.01378952,0.01512781,0.002436626,0.009412572,0.0005129965],"domain_scores_gemma":[0.8383292,0.07669931,0.06224957,0.003055833,0.01844908,0.001216994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002968797,0.000131565,0.7639623,0.06581573,0.0105042,0.0003918331,0.01024306,0.0004561328,0.001117969,0.0002750288,0.002816177,0.1413172],"study_design_scores_gemma":[0.0004887418,0.0008959019,0.9436517,0.02889021,0.01056794,0.0007522402,0.003648399,0.0006862966,0.0006879588,0.00008989953,0.009532234,0.0001083941],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8009948,0.185187,0.001031468,0.001101023,0.00008736465,0.001495795,0.006836696,0.00004662973,0.003219186],"genre_scores_gemma":[0.9558115,0.03834105,0.002218832,0.0005899768,0.00003128545,0.0005547462,0.002247515,0.00001595354,0.0001890225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07126763,"threshold_uncertainty_score":0.1417056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06098487476678312,"score_gpt":0.3718949081555471,"score_spread":0.310910033388764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}