{"id":"W2411876523","doi":"10.1136/annrheumdis-2015-eular.1840","title":"THU0427 Sustained Improvements in Skin Outcomes Following Certolizumab Pegol Treatment of Psoriatic Arthritis Patients with Prior Anti-TNF Exposure or Severe Skin Involvement at Baseline","year":2015,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Medicine; Certolizumab pegol; Psoriatic arthritis; Psoriasis; Dermatology Life Quality Index; Psoriasis Area and Severity Index; Internal medicine; Placebo; Clinical endpoint; Randomized controlled trial; Adalimumab; Body surface area; Gastroenterology; Surgery; Dermatology; Tumor necrosis factor alpha; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004983658,0.0001794513,0.0006229134,0.0001592979,0.000172769,0.0003994152,0.0001616772,0.0002524504,0.002144115],"category_scores_gemma":[0.0009841574,0.00009074155,0.0005162566,0.0002179875,0.0001087647,0.0003091705,0.00015552,0.0007733827,0.0003010891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002479094,"about_ca_system_score_gemma":0.0003386211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008322849,"about_ca_topic_score_gemma":0.001839382,"domain_scores_codex":[0.9996622,0.0001045256,0.00002603927,0.00004005883,0.00005767767,0.0001094847],"domain_scores_gemma":[0.999492,0.000104271,0.00015538,0.00003249594,0.00007443512,0.0001413092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.1315714,0.008600886,0.3166012,0.001001731,0.002918591,0.001041349,0.0003689805,0.00117447,0.04506163,0.0002072333,0.005150757,0.4863017],"study_design_scores_gemma":[0.004089606,0.04310596,0.9396662,0.00009990223,0.001178797,0.001031961,0.0003164773,0.001283329,0.005779731,0.000154884,0.003261939,0.0000312032],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962261,0.00183532,0.00007047705,0.0001247899,0.00004877968,0.00002664809,0.0002363735,0.00001691326,0.001414579],"genre_scores_gemma":[0.9988966,0.0002689869,0.00006720839,0.00007233867,0.00002907841,0.00001401199,0.0002009519,0.000001715421,0.0004491265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002144115,"threshold_uncertainty_score":0.007172823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02869060349835092,"score_gpt":0.286640104585152,"score_spread":0.2579495010868011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}