{"id":"W2413177871","doi":"10.1182/blood-2016-02-701029","title":"XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Child and Family Research Institute","funders":"ZonMw","keywords":"V(D)J recombination; Recombination; Genetics; Nucleotide; DNA; Biology; Ligation; Molecular biology; Chemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001692599,0.0006429143,0.0003293228,0.0007478711,0.0002164823,0.0002836264,0.00019786,0.0004743207,0.001457308],"category_scores_gemma":[0.0006305646,0.0001824955,0.000231412,0.0002071044,0.0004200057,0.0001833103,0.0001907983,0.0002507391,0.0002161342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002600597,"about_ca_system_score_gemma":0.0001225632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005747298,"about_ca_topic_score_gemma":0.0003259429,"domain_scores_codex":[0.999804,0.00003231516,0.00002634274,0.00006551735,0.00003263542,0.00003926255],"domain_scores_gemma":[0.999626,0.0001119694,0.0001362543,0.00002101239,0.00001923041,0.00008556567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001793509,0.0001691313,0.1947976,0.000116985,0.00008578174,0.01820765,0.0004445719,0.0005261372,0.7693109,0.0001846704,0.0001826933,0.01418031],"study_design_scores_gemma":[0.0001933839,0.002122657,0.6274808,0.00004039175,0.0002031438,0.1304408,0.000297874,0.001849831,0.2344615,0.0001632553,0.002708625,0.00003766929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992363,0.0001703302,0.0003052666,0.00001038471,0.000001751142,0.000003603758,0.00008776096,0.00001575318,0.0001687668],"genre_scores_gemma":[0.9994755,0.00006487047,0.0002366793,0.000008776366,0.000003116248,0.000002951434,0.00008370256,0.000004762699,0.0001196771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001457308,"threshold_uncertainty_score":0.004875183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006998140042039837,"score_gpt":0.2143446001706241,"score_spread":0.2073464601285842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}