{"id":"W2413218943","doi":"10.1042/cs103s128s","title":"Endothelin-1 (1-31) induces a thiorphan-sensitive release of eicosanoids via ETB receptors in the guinea pig perfused lung","year":2002,"lang":"en","type":"article","venue":"Clinical Science","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec","keywords":"Thiorphan; Thromboxane; Chemistry; Receptor; Agonist; Endothelin receptor; Prostacyclin; Endocrinology; Internal medicine; Thromboxane A2; Phosphoramidon; Guinea pig; Eicosanoid; Leukotriene; Endothelin 1; Pharmacology; Biology; Enzyme inhibitor; Arachidonic acid; Medicine; Biochemistry; Enzyme; Platelet","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004257126,0.0001813508,0.0004854269,0.0001936386,0.0001313429,0.00002657873,0.0005261244,0.0001508496,0.0001795022],"category_scores_gemma":[0.006436526,0.0001110048,0.0001878156,0.001453955,0.00136074,0.0001691617,0.00009960705,0.000640256,0.0001719278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006545251,"about_ca_system_score_gemma":0.0001733238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001081441,"about_ca_topic_score_gemma":0.000007668277,"domain_scores_codex":[0.9970888,0.0003427644,0.0007838393,0.0005408363,0.000764838,0.0004789474],"domain_scores_gemma":[0.9963472,0.002394214,0.0002174097,0.0006046374,0.0001868498,0.0002496413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001024312,0.005251687,0.1652609,0.0002400076,0.00009588635,0.0007173121,0.009158175,0.00004514979,0.549097,0.0008447718,0.01555257,0.2527122],"study_design_scores_gemma":[0.02912276,0.01146894,0.4185426,0.002374924,0.0008914464,0.0006985181,0.006240282,0.08242891,0.4240771,0.001644548,0.02014909,0.002360868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878368,0.0002667769,0.00008657652,0.002682061,0.000458875,0.0005363522,0.000004631627,0.00003587492,0.008092009],"genre_scores_gemma":[0.9956703,0.0002898154,0.0006040594,0.00244396,0.0003231647,0.00001492701,0.000001339655,0.00001249382,0.0006399205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2532817,"threshold_uncertainty_score":0.7705588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05075491937826235,"score_gpt":0.3493520867620731,"score_spread":0.2985971673838108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}