{"id":"W2413218943","doi":"10.1042/cs103s128s","title":"Endothelin-1 (1-31) induces a thiorphan-sensitive release of eicosanoids via ETB receptors in the guinea pig perfused lung","year":2002,"lang":"en","type":"article","venue":"Clinical Science","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec","keywords":"Thiorphan; Thromboxane; Chemistry; Receptor; Agonist; Endothelin receptor; Prostacyclin; Endocrinology; Internal medicine; Thromboxane A2; Phosphoramidon; Guinea pig; Eicosanoid; Leukotriene; Endothelin 1; Pharmacology; Biology; Enzyme inhibitor; Arachidonic acid; Medicine; Biochemistry; Enzyme; Platelet","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005074883,0.0005326802,0.0005999423,0.0002853174,0.0001921632,0.0002946463,0.0002649364,0.0007541152,0.001426954],"category_scores_gemma":[0.0002006463,0.0004277167,0.0006230744,0.0002043933,0.0004826192,0.0005207237,0.0002649657,0.001134258,0.0005134514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002640009,"about_ca_system_score_gemma":0.0002478432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003586903,"about_ca_topic_score_gemma":0.0005392416,"domain_scores_codex":[0.9996762,0.0000722773,0.00003156498,0.00006426428,0.00008750283,0.00006817341],"domain_scores_gemma":[0.9998325,0.00003591345,0.00003650682,0.00001979054,0.00001248042,0.0000627862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009738774,0.00002370242,0.00003005201,0.00002436338,0.000003121613,0.00008502099,0.000008544329,0.00000921316,0.999441,0.00002229894,0.000008553167,0.0002468326],"study_design_scores_gemma":[0.0001157956,0.002736818,0.01331725,0.00001667525,0.0000353174,0.0007503128,0.0000336745,0.000389378,0.9811956,0.00007882697,0.001320173,0.00001013427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858778,0.008646957,0.002673505,0.0003182679,0.0001473586,0.000156297,0.0002892492,0.00006258777,0.001828098],"genre_scores_gemma":[0.983124,0.006024995,0.006447305,0.0004014485,0.0001140941,0.000171599,0.0005395584,0.00002299149,0.003153877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001426954,"threshold_uncertainty_score":0.004773676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05075491937826235,"score_gpt":0.3493520867620731,"score_spread":0.2985971673838108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}