{"id":"W2413327718","doi":"10.1093/aob/mcw089","title":"Targeted Genome Editing Using Site-Specific Nucleases, ZFNs, TALENs, and the CRISPR/Cas9 system Takashi Yamamoto (ed.).","year":2016,"lang":"en","type":"article","venue":"Annals of Botany","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"SNC-Lavalin (Canada)","funders":"","keywords":"Transcription activator-like effector nuclease; Biology; CRISPR; Genome editing; Cas9; Genetics; Zinc finger nuclease; Computational biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003687009,0.0001894796,0.0002454825,0.00003696108,0.000107197,0.00002913593,0.0001676873,0.0001154819,0.00002890698],"category_scores_gemma":[0.00008445428,0.0001262078,0.0001253836,0.00006637425,0.0001677256,0.000006377074,0.0001356108,0.00006044669,0.00001058499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008462343,"about_ca_system_score_gemma":0.0000187611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002340733,"about_ca_topic_score_gemma":0.000004762064,"domain_scores_codex":[0.9988144,0.00006587422,0.0003245519,0.0003193133,0.0001553563,0.0003205214],"domain_scores_gemma":[0.9991922,0.00003477674,0.0001351818,0.0004043294,0.0001342848,0.00009926948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009395948,0.00001426382,0.0003737074,0.00005656461,0.00006002693,0.000006456088,0.00005258099,0.00005926105,0.995423,0.0001551634,0.002347515,0.00135749],"study_design_scores_gemma":[0.002753506,0.0002866928,0.007116939,0.0003980178,0.00008917075,0.0001571608,0.0009045721,0.0008144939,0.8048806,0.00005377658,0.1818105,0.0007346208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9665635,0.02676513,0.005458216,0.0003586121,0.0001949865,0.0002226545,0.0001024403,0.00002372932,0.0003107828],"genre_scores_gemma":[0.9963809,0.002205153,0.0004980813,0.0001237026,0.0005967617,0.000007585921,0.000008725008,0.0000362208,0.0001429046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1905425,"threshold_uncertainty_score":0.5146605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01695390734224204,"score_gpt":0.2807785516212812,"score_spread":0.2638246442790391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}