{"id":"W2413339907","doi":"10.1385/1-59259-284-8:055","title":"Identification of Mutations in mtDNA from Patients Suffering Mitochondrial Diseases","year":2003,"lang":"en","type":"article","venue":"Mitochondrial DNA","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Oxidoreductase; Cytochrome c oxidase; Protein subunit; Biology; Mitochondrial DNA; Gene; Nuclear gene; NADH dehydrogenase; Mitochondrion; Respiratory chain; MT-RNR1; Biochemistry; Inner membrane; Molecular biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005996918,0.0002112447,0.0002706911,0.0001415044,0.00007317916,0.00002807587,0.0001959021,0.000232869,0.0001720981],"category_scores_gemma":[0.0009319211,0.000226299,0.0001550223,0.0002187744,0.00009857913,0.00001497105,0.0000466622,0.0001103819,0.000045288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002752142,"about_ca_system_score_gemma":0.00009345101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006702291,"about_ca_topic_score_gemma":0.0001640844,"domain_scores_codex":[0.9980646,0.0002649673,0.0006475036,0.0005427895,0.0002123294,0.0002678122],"domain_scores_gemma":[0.9989914,0.00005493663,0.0002250421,0.0004817178,0.0001378116,0.0001091321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002830203,0.0002709082,0.01688001,0.00001210411,0.0000283883,0.00000208499,0.0001140756,0.00007839609,0.9805557,0.0003458839,0.001136328,0.000293125],"study_design_scores_gemma":[0.005763096,0.0003739583,0.03608622,0.00003501433,0.00008759847,0.000002920382,0.000153524,0.00004712337,0.9357228,0.001354715,0.01984882,0.0005242235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869297,0.0001701238,0.006405963,0.00002484279,0.005079448,0.000511181,0.0002852871,0.00001913682,0.0005743545],"genre_scores_gemma":[0.9953951,0.00003105308,0.001812151,0.00007101511,0.0008163126,0.0001036344,0.00115538,0.00003698843,0.0005783785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0448329,"threshold_uncertainty_score":0.9228207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008236382716025292,"score_gpt":0.2342486660273245,"score_spread":0.2260122833112992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}