{"id":"W2413345150","doi":"10.18632/oncotarget.9818","title":"Schlafen2 mutation unravels a role for chronic ER stress in the loss of T cell quiescence","year":2016,"lang":"en","type":"article","venue":"Oncotarget","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Israel Science Foundation; Israel Cancer Research Fund; Concern Foundation","keywords":"Unfolded protein response; XBP1; Cell biology; Immune system; Biology; Cell growth; Mechanism (biology); Cell; Immunology; Endoplasmic reticulum; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000861857,0.0002820827,0.0001637925,0.0001815084,0.000136415,0.0002469125,0.0001706445,0.0004147419,0.001348441],"category_scores_gemma":[0.0001146878,0.00009986268,0.0001922282,0.0001150491,0.0002440282,0.0002851863,0.0001950351,0.0006294508,0.0002677487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000186763,"about_ca_system_score_gemma":0.00009316343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002247104,"about_ca_topic_score_gemma":0.0003913243,"domain_scores_codex":[0.9999385,0.000008335104,0.000007798627,0.00001600629,0.000013748,0.00001566274],"domain_scores_gemma":[0.9999053,0.00002571208,0.00003354476,0.000008532914,0.000006102946,0.00002082192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002260609,0.00002575522,0.002710255,0.00003545304,0.000007342318,0.003090623,0.00003857176,0.0000938774,0.9901201,0.0002349574,0.0001872645,0.003229898],"study_design_scores_gemma":[0.00006999021,0.0004940897,0.03874623,0.00004422043,0.00005683579,0.01826506,0.0003296736,0.005033101,0.9266133,0.0006918822,0.009626091,0.00002945904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951431,0.0009815098,0.002249036,0.000308554,0.00004207259,0.00001496452,0.0001807691,0.0000758231,0.001004222],"genre_scores_gemma":[0.9973537,0.0004839237,0.0009494146,0.0001086367,0.00001570101,0.000007401131,0.0001759015,0.00001371118,0.0008915574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001348441,"threshold_uncertainty_score":0.004510939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008219205636245347,"score_gpt":0.2370971071821963,"score_spread":0.228877901545951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}