{"id":"W2413354451","doi":"10.1016/j.cjca.2015.07.322","title":"ALTERED HEME METABOLISM IN THE HEART: DOES STRESS ELICIT ANATOMICALLY DISTINCT DIFFERENCES IN MOLECULAR SIGNALLING THAT COULD IMPACT OUTCOMES IN RIGHT AND LEFT VENTRICULAR HEART FAILURE?","year":2015,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saint John Regional Hospital","funders":"","keywords":"Medicine; Heart failure; Heme oxygenase; Internal medicine; Heme; Cardiology; HMOX1; Endocrinology; Hypoxia (environmental); Enzyme; Biochemistry; Biology; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002982202,0.0002538399,0.000564836,0.0001613288,0.0002644677,0.0006812324,0.0002908974,0.0008328656,0.001369508],"category_scores_gemma":[0.0005144741,0.0001694581,0.0002177976,0.0001169715,0.0007483745,0.0005376234,0.0004233479,0.0008724187,0.0001708752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000380562,"about_ca_system_score_gemma":0.0003838077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00109933,"about_ca_topic_score_gemma":0.002128279,"domain_scores_codex":[0.9998554,0.0000294633,0.000006826576,0.00002650126,0.000021036,0.00006081838],"domain_scores_gemma":[0.9997428,0.00004252145,0.00006441234,0.00002799208,0.00002484795,0.00009754144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01085891,0.0007309488,0.06851806,0.000471867,0.0002547096,0.002237239,0.001114778,0.0005253337,0.8563636,0.004800702,0.001482684,0.05264116],"study_design_scores_gemma":[0.0001856915,0.002030657,0.963479,0.0001154004,0.0001257017,0.001427151,0.002310009,0.0006278622,0.023276,0.004611464,0.001759226,0.00005184454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988227,0.00634531,0.000981888,0.002201416,0.0001455527,0.00002050953,0.0001739688,0.00001536383,0.00188894],"genre_scores_gemma":[0.9967445,0.001886041,0.0002090124,0.0003756149,0.000102584,0.00001195359,0.00007303055,0.000006172543,0.0005910132],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001369508,"threshold_uncertainty_score":0.004581451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01171938680975512,"score_gpt":0.2431269803237663,"score_spread":0.2314075935140112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}