{"id":"W2413798844","doi":"10.1177/1934578x1501001005","title":"Isolation of Phomopsolide A and 6(E)-Phomopsolide A as Antimycobacterial Products from an Unidentified Endophyte of the Canadian Medicinal Plant <i>Heracleum maximum</i>","year":2015,"lang":"en","type":"article","venue":"Natural Product Communications","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saint John Regional Hospital; Atlantic Cancer Research Institute; Université de Moncton; University of New Brunswick","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Antimycobacterial; Endophyte; Isolation (microbiology); Traditional medicine; Biology; Bioassay; Medicinal plants; Mycobacterium tuberculosis; Fractionation; Botany; Microbiology; Tuberculosis; Chemistry; Medicine; Chromatography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004436195,0.0001766335,0.0002277715,0.00007304265,0.0002024335,0.00003072269,0.0008434138,0.0001089767,0.000006126934],"category_scores_gemma":[0.0009302956,0.0001347243,0.00004745752,0.0002793258,0.000352346,0.00003215444,0.000436091,0.0003093227,0.000001761198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003493665,"about_ca_system_score_gemma":0.0006433148,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.05742381,"about_ca_topic_score_gemma":0.09316408,"domain_scores_codex":[0.9985238,0.0002619745,0.0003671191,0.000393124,0.0002398112,0.0002141826],"domain_scores_gemma":[0.9969533,0.00002423803,0.0002799694,0.001978438,0.0006161529,0.0001479017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003269071,0.0001012416,0.005250315,0.00003377373,0.00009402938,8.994861e-7,0.0005310205,0.000008136174,0.9872465,0.0003670709,0.002309667,0.003730509],"study_design_scores_gemma":[0.001559525,0.0003741886,0.07363319,0.00009129005,0.0001487956,0.0001138142,0.0002026781,0.0002652664,0.8700615,0.001910946,0.05119736,0.0004414153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866106,0.005222447,0.000001299303,0.006106432,0.0007290558,0.0004915358,0.0001641877,0.00001007352,0.0006643962],"genre_scores_gemma":[0.9959702,0.0003252386,0.001890342,0.00019371,0.0003791851,0.000009423599,0.0008957424,0.00001836354,0.0003177884],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1171849,"threshold_uncertainty_score":0.9488529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02126829852984388,"score_gpt":0.2718933258092548,"score_spread":0.250625027279411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}