{"id":"W2413798844","doi":"10.1177/1934578x1501001005","title":"Isolation of Phomopsolide A and 6(E)-Phomopsolide A as Antimycobacterial Products from an Unidentified Endophyte of the Canadian Medicinal Plant <i>Heracleum maximum</i>","year":2015,"lang":"en","type":"article","venue":"Natural Product Communications","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saint John Regional Hospital; Atlantic Cancer Research Institute; Université de Moncton; University of New Brunswick","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Antimycobacterial; Endophyte; Isolation (microbiology); Traditional medicine; Biology; Bioassay; Medicinal plants; Mycobacterium tuberculosis; Fractionation; Botany; Microbiology; Tuberculosis; Chemistry; Medicine; Chromatography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006998513,0.000407204,0.0001810944,0.0003622408,0.0002894182,0.0002383471,0.0001158001,0.000226848,0.0008702368],"category_scores_gemma":[0.0001186448,0.0001045382,0.0002041218,0.0003056078,0.0002628649,0.0002096725,0.0001560396,0.0003776268,0.0001941365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000371896,"about_ca_system_score_gemma":0.0008921756,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009998054,"about_ca_topic_score_gemma":0.0198441,"domain_scores_codex":[0.9999449,0.000006651504,0.00000299683,0.00001137227,0.00001672429,0.00001735048],"domain_scores_gemma":[0.9999285,0.00001100485,0.00001077967,0.000005949072,0.00001759238,0.00002623222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008732669,0.000009084883,0.0002631837,0.00003040808,0.000004602559,0.0001221643,0.00001603896,0.0000244972,0.9973993,0.00003871796,0.00002391955,0.001980714],"study_design_scores_gemma":[0.0000324452,0.0006646243,0.03052804,0.00001457441,0.00003749493,0.0007403839,0.0001237229,0.0002098984,0.9608715,0.00008418984,0.006679597,0.00001364212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893188,0.00279312,0.002440219,0.0001520061,0.00002251449,0.0001156219,0.001170895,0.00004171533,0.00394519],"genre_scores_gemma":[0.9878854,0.001591381,0.005056221,0.0001094558,0.00001743485,0.00003819782,0.001761577,0.00001842597,0.003522054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9900019,"threshold_uncertainty_score":0.0198797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02126829852984388,"score_gpt":0.2718933258092548,"score_spread":0.250625027279411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}