{"id":"W2414144199","doi":"10.1097/j.pain.0000000000000273","title":"COMT gene locus","year":2015,"lang":"es","type":"article","venue":"Pain","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"U.S. National Library of Medicine; National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Neurological Disorders and Stroke; University of Florida","keywords":"Catechol-O-methyl transferase; Gene isoform; Biology; rs4680; Allele; Phenotype; Neuroscience; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001311247,0.0001202309,0.00009590446,0.00003222064,0.00004566896,0.00003730403,0.00007997172,0.000186927,0.00005538465],"category_scores_gemma":[0.000344125,0.0001185257,0.00006444649,0.00007231381,0.00004661201,0.000002154113,0.00004921909,0.00005586612,0.0001798431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002398771,"about_ca_system_score_gemma":0.00008324518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001365367,"about_ca_topic_score_gemma":0.000002914825,"domain_scores_codex":[0.9989764,0.0003597655,0.0001435272,0.0002206765,0.0001282715,0.00017136],"domain_scores_gemma":[0.99943,0.00001668902,0.00005694382,0.0002198608,0.0001262491,0.0001502617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005745418,0.0004041329,0.01626066,0.0001146872,0.0002351742,0.00002156624,0.000407478,0.002489643,0.2833203,0.001860337,0.5092577,0.1850538],"study_design_scores_gemma":[0.0006885158,0.0003089709,0.0003627225,0.00001251868,0.00001552609,0.000009429868,0.0001451978,0.008201913,0.07314309,0.0001591641,0.9167268,0.0002261867],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.446602,0.01275349,0.4839973,0.007393491,0.007458974,0.000795985,0.00009874719,0.0001241607,0.04077576],"genre_scores_gemma":[0.9922219,0.0001137495,0.0002434376,0.000847807,0.001570331,0.000007122079,0.0002639958,0.00001878296,0.004712882],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5456198,"threshold_uncertainty_score":0.4833336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02127729144824836,"score_gpt":0.2503157378182747,"score_spread":0.2290384463700263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}