{"id":"W2414204484","doi":"10.1038/srep13730","title":"Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Trace Elements in Health","field":"Nursing","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; Journal of Gastroenterology and Hepatology Foundation; Alzheimer Society; McGill University","keywords":"Methylene blue; Cysteine; Caspase; Recombinant DNA; Chemistry; Apoptosis; Biochemistry; Transfection; Molecular biology; Biology; Programmed cell death; Enzyme; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001636334,0.0002898166,0.0001440029,0.0001736756,0.0001059479,0.0001389328,0.0002055067,0.0003450086,0.001703329],"category_scores_gemma":[0.0001585338,0.0001067359,0.0002004958,0.0000845075,0.000213612,0.000193062,0.0001660624,0.0003505728,0.0002308719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001416366,"about_ca_system_score_gemma":0.0001471586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003662594,"about_ca_topic_score_gemma":0.0006661151,"domain_scores_codex":[0.9999014,0.00002428822,0.000007385444,0.00001736055,0.00003074693,0.00001876535],"domain_scores_gemma":[0.9999224,0.00002383401,0.0000244402,0.000009443443,0.00001062237,0.000009232738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001217322,0.00002385442,0.0001293804,0.00005055436,0.000007715522,0.00002506552,0.00001292246,0.00006324939,0.9964953,0.0001210277,0.00003728146,0.002911873],"study_design_scores_gemma":[0.00002189961,0.001001913,0.0007536887,0.000006266634,0.000008978053,0.0001224594,0.000008863914,0.000218854,0.9959192,0.00006110733,0.001874438,0.000002492944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831594,0.005829733,0.00694351,0.0002618527,0.00003728948,0.00004640945,0.00009046504,0.0001019265,0.003529379],"genre_scores_gemma":[0.9914106,0.002384476,0.003642471,0.00009988431,0.00001463103,0.00001739308,0.0000938184,0.00001074559,0.00232591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001703329,"threshold_uncertainty_score":0.005698204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03134215240710247,"score_gpt":0.2994922705019196,"score_spread":0.2681501180948171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}