{"id":"W2414235983","doi":"10.1371/journal.ppat.1005690","title":"Leishmania major Promastigotes Evade LC3-Associated Phagocytosis through the Action of GP63","year":2016,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Universitaire Stichting; McMaster University","keywords":"Phagosome; Phagocytosis; Cell biology; NADPH oxidase; Phagolysosome; Leishmania; Internalization; Autophagy; Biology; Microbiology; Intracellular parasite; Chemistry; Reactive oxygen species; Intracellular; Biochemistry; Apoptosis; Parasite hosting; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001545453,0.0002466887,0.0002402433,0.0001348534,0.0001514171,0.0002985869,0.0001209103,0.0002892988,0.0005222544],"category_scores_gemma":[0.0001179281,0.0000837097,0.0002596918,0.00008938624,0.0002259368,0.0002042688,0.0003048507,0.0004465594,0.0002368804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001743266,"about_ca_system_score_gemma":0.000172006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003002486,"about_ca_topic_score_gemma":0.0005064117,"domain_scores_codex":[0.9998755,0.00002466378,0.00001035369,0.00001462067,0.00003872409,0.00003610567],"domain_scores_gemma":[0.9999511,0.000005815419,0.00001484798,0.000007773434,0.000009625062,0.00001074301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000118311,0.00002510063,0.0001983952,0.00005413925,0.000004576876,0.00009093332,0.00001721792,0.00002173593,0.9971133,0.0001465905,0.00004106546,0.002168601],"study_design_scores_gemma":[0.00006627617,0.0006890016,0.01257338,0.00002527834,0.00002597084,0.0009831527,0.00005684407,0.0008919047,0.979536,0.0003187701,0.004827932,0.000005519179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887755,0.005313024,0.003103493,0.0003171609,0.00002634355,0.00003840677,0.0001184543,0.00007620222,0.002231487],"genre_scores_gemma":[0.994951,0.001686333,0.001464589,0.00009915011,0.00001244961,0.0000232636,0.00009609656,0.000009656079,0.001657572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005222544,"threshold_uncertainty_score":0.001747131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04769940383388505,"score_gpt":0.2921388037112096,"score_spread":0.2444393998773245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}