{"id":"W2414270108","doi":"10.1016/j.cyto.2016.06.011","title":"Interleukin-21-dependent modulation of T cell antigen receptor reactivity towards low affinity peptide ligands in autoreactive CD8+ T lymphocytes","year":2016,"lang":"en","type":"article","venue":"Cytokine","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Cytotoxic T cell; T-cell receptor; Lymphocytic choriomeningitis; Interleukin 21; CD8; NOD mice; T cell; Adoptive cell transfer; Antigen; Immunology; Molecular biology; Immune system; Autoimmunity; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001893478,0.000333568,0.0002006798,0.0001869023,0.0001795261,0.0003467861,0.0001766924,0.0003020315,0.001647217],"category_scores_gemma":[0.0002883859,0.0001443888,0.000262908,0.0001369234,0.0002859113,0.0002281645,0.000213798,0.0007708108,0.0004373874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002088927,"about_ca_system_score_gemma":0.0001413697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002143792,"about_ca_topic_score_gemma":0.0004635973,"domain_scores_codex":[0.9996941,0.00008556644,0.00002480391,0.00003374484,0.00004406977,0.0001177494],"domain_scores_gemma":[0.9997929,0.00007612829,0.00002980675,0.00003466591,0.00001968021,0.0000468324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007453734,0.00005195973,0.0002323567,0.00001933763,0.000003167137,0.00007672833,0.000015256,0.00004009305,0.9978339,0.00004051516,0.00002345896,0.0009177934],"study_design_scores_gemma":[0.00007770708,0.0007856615,0.01367363,0.000006792204,0.0000277921,0.0003641339,0.0000373501,0.0007926912,0.9831786,0.0001000341,0.0009481474,0.000007538782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983857,0.0004025204,0.0003129555,0.00002435312,0.00002426072,0.000009126395,0.0000539834,0.00001305636,0.0007740882],"genre_scores_gemma":[0.9982436,0.0002148389,0.0003106295,0.0000293883,0.00002092875,0.0000190606,0.0001397918,0.000007719769,0.001014115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001647217,"threshold_uncertainty_score":0.005510449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01082361883974703,"score_gpt":0.2249561500857958,"score_spread":0.2141325312460488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}