{"id":"W2415048633","doi":"10.1007/978-1-60327-355-8_8","title":"Mapping Genomic Targets of DNA Helicases by Chromatin Immunoprecipitation in Saccharomyces cerevisiae","year":2009,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Helicase; Chromatin immunoprecipitation; RecQ helicase; Biology; Control of chromosome duplication; DNA replication; Saccharomyces cerevisiae; Chromatin; ChIP-sequencing; Minichromosome maintenance; Cell biology; DNA; Genetics; Chromatin remodeling; Gene; Gene expression; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001473577,0.0002375988,0.000182275,0.0004000337,0.0001667081,0.0004523219,0.0002299803,0.0001730517,0.00102479],"category_scores_gemma":[0.0001411645,0.0003206695,0.0002850694,0.0002585837,0.0001976486,0.000116629,0.0002324008,0.0004192684,0.0007558182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004954668,"about_ca_system_score_gemma":0.0002732513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004131535,"about_ca_topic_score_gemma":0.00889165,"domain_scores_codex":[0.9999181,0.000007741263,0.000009059815,0.00002645918,0.00002924745,0.000009441836],"domain_scores_gemma":[0.9998982,0.00002793706,0.0000181852,0.00001962282,0.00001930392,0.00001663549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005015716,0.00001340117,0.0005330777,0.00003491211,0.000007705395,0.00002848185,0.00001701496,0.0002152433,0.9968316,0.0001397802,0.00009186395,0.002036821],"study_design_scores_gemma":[0.0000183583,0.00005678889,0.007179683,0.000008288285,0.00002837667,0.00009957489,0.0000549878,0.002275895,0.9837203,0.0001263919,0.006421207,0.00001007057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9407643,0.004190655,0.04388871,0.0003441937,0.000110731,0.00009117625,0.006830616,0.0007695238,0.003010135],"genre_scores_gemma":[0.9389884,0.002744675,0.04262799,0.0002030082,0.00001855243,0.00008585233,0.009122523,0.0002282428,0.005980607],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.004131535,"threshold_uncertainty_score":0.008214951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01192557821820234,"score_gpt":0.3353262096168108,"score_spread":0.3234006313986085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}