{"id":"W2415223489","doi":"10.1007/978-1-4939-3387-7_37","title":"Methods and Protocols for Developing Prion Vaccines","year":2016,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Immunogenicity; Epitope; Immune system; Computational biology; Virology; Biology; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002995837,0.002589808,0.001180123,0.003985159,0.002229448,0.001209523,0.002691942,0.001974164,0.01113406],"category_scores_gemma":[0.00198944,0.002235025,0.001243359,0.00227702,0.001166936,0.001719661,0.001273826,0.005826359,0.01229725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000949033,"about_ca_system_score_gemma":0.001329771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008685891,"about_ca_topic_score_gemma":0.001868728,"domain_scores_codex":[0.9978755,0.0005484348,0.0002301398,0.000249132,0.0008660381,0.0002307895],"domain_scores_gemma":[0.998683,0.0003129723,0.0001316382,0.0005248683,0.0002625329,0.00008490727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002457077,0.0004293307,0.0002362274,0.001586184,0.00005708014,0.0003321393,0.0003891359,0.0009480373,0.8797031,0.01688913,0.01375861,0.08542532],"study_design_scores_gemma":[0.000128874,0.0004925216,0.0006766034,0.0002251426,0.00008655238,0.0008831088,0.00007464335,0.00153768,0.7633147,0.009210937,0.2232232,0.0001460944],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.01978177,0.01404792,0.930499,0.0011802,0.001406361,0.006007801,0.004901551,0.00356739,0.01860808],"genre_scores_gemma":[0.04791856,0.0260019,0.8584325,0.0009869133,0.0004084187,0.01795464,0.01114797,0.0008986574,0.03625039],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.01113406,"threshold_uncertainty_score":0.03724712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03903154180356549,"score_gpt":0.478385620510852,"score_spread":0.4393540787072865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}