{"id":"W2415828882","doi":"10.1007/978-1-4939-0473-0_41","title":"Signature-Tagged Mutagenesis","year":2014,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Insertional mutagenesis; Mutagenesis; Biology; Virulence; Mutant; Phenotype; Gene; Genetics; Genome; Computational biology; Population; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001138478,0.00170723,0.001027082,0.0009407489,0.001035033,0.0006757643,0.001744146,0.001147924,0.01252045],"category_scores_gemma":[0.0005933631,0.000972903,0.001074454,0.0008829865,0.0007392255,0.0004494094,0.0009118228,0.003173142,0.007863485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008405782,"about_ca_system_score_gemma":0.001312472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001032421,"about_ca_topic_score_gemma":0.003292419,"domain_scores_codex":[0.9983419,0.0003032045,0.0001805833,0.0003598744,0.0004748282,0.0003396374],"domain_scores_gemma":[0.9992035,0.0001313924,0.00008230776,0.000345922,0.00009628839,0.000140625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002982214,0.0001292281,0.0002097543,0.0001476987,0.00002342273,0.000100037,0.00004059976,0.0001732675,0.9845166,0.001786361,0.001808939,0.01076589],"study_design_scores_gemma":[0.00003653325,0.00009590512,0.0004375647,0.000009378176,0.00002148802,0.0002523315,0.00001008052,0.0006371267,0.9842434,0.0001923489,0.01404712,0.00001684876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.3664505,0.001394266,0.5578167,0.001319614,0.001594171,0.00322864,0.01758727,0.0152877,0.03532118],"genre_scores_gemma":[0.6451909,0.001815593,0.2498737,0.001345231,0.00008878415,0.001953054,0.02816813,0.003267345,0.06829729],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.01252045,"threshold_uncertainty_score":0.04188514,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00983364260513052,"score_gpt":0.3328258186153264,"score_spread":0.3229921760101959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}