{"id":"W2415959686","doi":"10.1002/glia.23007","title":"Critical data‐based re‐evaluation of minocycline as a putative specific microglia inhibitor","year":2016,"lang":"en","type":"review","venue":"Glia","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":196,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute on Aging","keywords":"Minocycline; Microglia; Biology; Neuroscience; Bioinformatics; Antibiotics; Pharmacology; Immunology; Inflammation; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001206127,0.0004540873,0.0009817622,0.0003406577,0.0001295553,0.0001046054,0.0008491028,0.0002538055,0.001453735],"category_scores_gemma":[0.005816611,0.0003538642,0.0002539735,0.0004326017,0.0002160091,0.0003480638,0.0002165014,0.0003427923,0.001747939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009012731,"about_ca_system_score_gemma":0.0006533319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001043236,"about_ca_topic_score_gemma":0.000001311684,"domain_scores_codex":[0.9939838,0.001944395,0.001204728,0.001271673,0.001270972,0.0003244033],"domain_scores_gemma":[0.9959922,0.00143514,0.0006674784,0.001401969,0.0003440536,0.0001591686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004062842,0.0002090104,5.675053e-8,0.00255911,0.00001282055,0.00007211146,0.00004978964,0.000002707964,0.148855,0.006657338,0.009177024,0.8323644],"study_design_scores_gemma":[0.0004952922,0.00009004764,1.217695e-7,0.001910115,0.0002399767,0.0000301323,0.000003078365,0.0004197651,0.2403827,0.0006029592,0.7555029,0.0003228991],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002600821,0.9834202,0.002494799,0.0007137694,0.004139168,0.003163734,0.003742582,0.0002328666,0.001832797],"genre_scores_gemma":[0.0003991798,0.9960675,0.001015689,0.0004475832,0.0006894892,0.0001299482,0.0004297233,0.0001092857,0.0007115745],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8320415,"threshold_uncertainty_score":0.9998913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3092491518119257,"score_gpt":0.4452920003390428,"score_spread":0.1360428485271171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}