{"id":"W2416181174","doi":"10.1182/blood.v122.21.686.686","title":"Patient Outcomes By Prior Therapies and Depth Of Response: Analysis Of MM-003, a Phase 3 Study Comparing Pomalidomide + Low-Dose Dexamethasone (POM + LoDEX) Vs High-Dose Dexamethasone (HiDEX) In Relapsed/Refractory Multiple Myeloma (RRMM)","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Princess Margaret Cancer Centre; Vancouver General Hospital","funders":"","keywords":"Pomalidomide; Medicine; Lenalidomide; Tolerability; Clinical endpoint; Internal medicine; Dexamethasone; Phases of clinical research; Neutropenia; Bortezomib; Refractory (planetary science); Progressive disease; Population; Multiple myeloma; Surgery; Urology; Oncology; Randomized controlled trial; Adverse effect; Clinical trial; Toxicity; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002233018,0.0006967557,0.001237017,0.0003608777,0.0003583454,0.0008118079,0.0007068333,0.0007114337,0.003280816],"category_scores_gemma":[0.00112653,0.0003202784,0.002256854,0.0005378443,0.0005872443,0.0006278759,0.0004521563,0.001738975,0.0003890035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008995355,"about_ca_system_score_gemma":0.0008770157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006997259,"about_ca_topic_score_gemma":0.001248737,"domain_scores_codex":[0.9990103,0.0004930133,0.00007336443,0.0001612074,0.0001335614,0.0001284564],"domain_scores_gemma":[0.9986689,0.0002524954,0.0004072496,0.00007232445,0.00004976208,0.0005493045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8477942,0.01372002,0.09488522,0.0003635801,0.00288484,0.0001993229,0.0001593384,0.001547384,0.009822103,0.0001647347,0.001225741,0.0272335],"study_design_scores_gemma":[0.175679,0.4360503,0.3679323,0.00009232063,0.003964851,0.0007362665,0.0002255692,0.005004898,0.005399746,0.0007587421,0.004063346,0.0000927795],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968517,0.000930517,0.0001604589,0.00008908355,0.00001756037,0.0003991209,0.001043268,0.00001327307,0.0004950597],"genre_scores_gemma":[0.9970505,0.0002531622,0.0003350676,0.0001876274,0.0000367014,0.0005317731,0.001053287,0.000005441273,0.0005464216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003280816,"threshold_uncertainty_score":0.01180947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02520003681151295,"score_gpt":0.3113322676816826,"score_spread":0.2861322308701696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}