{"id":"W2416337535","doi":"10.1021/nn5058886","title":"Binding Forces of <i>Streptococcus mutans</i> P1 Adhesin","year":2015,"lang":"en","type":"article","venue":"ACS Nano","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Dental and Craniofacial Research; Fonds De La Recherche Scientifique - FNRS","keywords":"Bacterial adhesin; Streptococcus mutans; Force spectroscopy; Adhesion; Biophysics; Chemistry; Fibronectin; Microbiology; Glycoprotein; Dental plaque; Extracellular matrix; Molecule; Bacteria; Virulence; Biochemistry; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001824261,0.000329991,0.0002515221,0.000243369,0.0004015239,0.0003339072,0.0002812347,0.0004001767,0.001200364],"category_scores_gemma":[0.0004495448,0.0002094565,0.0001778606,0.000164717,0.0003206016,0.0003372195,0.0002886912,0.000453867,0.0002266299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004183603,"about_ca_system_score_gemma":0.0002211204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00299054,"about_ca_topic_score_gemma":0.001482353,"domain_scores_codex":[0.9997413,0.00002075208,0.000007917813,0.0000447986,0.0001301194,0.00005522221],"domain_scores_gemma":[0.9997303,0.0001292097,0.00005853315,0.00001224806,0.00004125854,0.00002850548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004432961,0.00003125979,0.0009957526,0.00008974398,0.00001476287,0.00009406999,0.0001080485,0.001021728,0.9924636,0.0003470663,0.0002507657,0.004538792],"study_design_scores_gemma":[0.00001359105,0.0002413056,0.02404934,0.00002053697,0.00002108535,0.0001728924,0.0002357475,0.0338665,0.9378427,0.0003320401,0.003162051,0.00004211442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950821,0.0007279338,0.002198048,0.0001415163,0.00002930523,0.00001434633,0.0001149872,0.00005912433,0.001632656],"genre_scores_gemma":[0.9976302,0.0004800886,0.001136364,0.00004990503,0.00001290696,0.00001900101,0.00006709445,0.000008018794,0.0005963141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00299054,"threshold_uncertainty_score":0.005946279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04491330708142563,"score_gpt":0.3100670120945928,"score_spread":0.2651537050131672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}