{"id":"W2416337535","doi":"10.1021/nn5058886","title":"Binding Forces of <i>Streptococcus mutans</i> P1 Adhesin","year":2015,"lang":"en","type":"article","venue":"ACS Nano","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Dental and Craniofacial Research; Fonds De La Recherche Scientifique - FNRS","keywords":"Bacterial adhesin; Streptococcus mutans; Force spectroscopy; Adhesion; Biophysics; Chemistry; Fibronectin; Microbiology; Glycoprotein; Dental plaque; Extracellular matrix; Molecule; Bacteria; Virulence; Biochemistry; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000078078,0.000111501,0.0002269061,0.0001043123,0.00003842133,0.000008911263,0.00004833706,0.00007214607,0.00009290504],"category_scores_gemma":[0.00009280637,0.00008609021,0.00007188373,0.0003357162,0.00005497598,0.00007509658,0.00002759465,0.00006022415,0.0001258606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006321691,"about_ca_system_score_gemma":0.00009734785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001317686,"about_ca_topic_score_gemma":0.000008806161,"domain_scores_codex":[0.9992781,0.00001528873,0.0002058417,0.0001624294,0.0001655106,0.0001728387],"domain_scores_gemma":[0.9993569,0.00004027149,0.00007920536,0.0002515261,0.000128095,0.0001439567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000138739,0.000680765,0.8698186,0.00006497998,0.0003042222,0.0000806185,0.0003780235,0.000008539183,0.1050971,0.0005832117,0.007686966,0.0151583],"study_design_scores_gemma":[0.005046039,0.001447015,0.01408571,0.000213478,0.0002924516,0.00009188467,0.000452884,0.00001466499,0.9519008,0.0004267298,0.02582369,0.0002046378],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9752383,0.0001580269,0.00003632415,0.0001119238,0.0001784772,0.0003812119,0.00001414338,0.00005976647,0.02382177],"genre_scores_gemma":[0.9967819,0.00001410597,0.000306597,0.00006034666,0.00007268049,0.00004662341,0.0000241831,0.00001505094,0.002678493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8557329,"threshold_uncertainty_score":0.3510657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04491330708142563,"score_gpt":0.3100670120945928,"score_spread":0.2651537050131672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}