{"id":"W2416519609","doi":"10.1385/1-59259-050-0:121","title":"Fluorescence Measurements of Ca&lt;sup&gt;2+&lt;/sup&gt; Binding to Domain VI of Calpain","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Context (archaeology); Binding constant; Calpain; Binding site; Chemistry; Binding domain; Fluorescence; Biophysics; Binding energy; Molecule; Stereochemistry; Crystallography; Biochemistry; Physics; Biology; Enzyme; Atomic physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002192066,0.0002676535,0.0002677507,0.0002272682,0.0003365359,0.0002925388,0.0005806938,0.0006057217,0.002495004],"category_scores_gemma":[0.0004041001,0.0001457898,0.0001455382,0.0003962632,0.0003319748,0.0003583962,0.0002587331,0.001113837,0.0005443596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006207257,"about_ca_system_score_gemma":0.000149442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001403903,"about_ca_topic_score_gemma":0.0008495533,"domain_scores_codex":[0.9998031,0.000018992,0.000006832705,0.00006014155,0.00005924207,0.00005171425],"domain_scores_gemma":[0.9998071,0.0000515525,0.00003781667,0.00002056033,0.00003451114,0.00004851581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001382661,0.00003430741,0.0002400787,0.00002791778,0.000003764791,0.00003281832,0.00003709431,0.00009179257,0.9976114,0.0002472019,0.0001698396,0.001365467],"study_design_scores_gemma":[0.00001978208,0.0001251865,0.0046741,0.000005267838,0.000006260762,0.0001322558,0.00002794564,0.002544288,0.9910777,0.0001062919,0.001275007,0.000006025132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9612995,0.0009988417,0.0282952,0.0002968372,0.00003666148,0.00004774623,0.0005815617,0.0003291481,0.008114495],"genre_scores_gemma":[0.9716323,0.0006239745,0.01644241,0.000228029,0.00002031522,0.00008844736,0.0007114849,0.00006791305,0.01018501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002495004,"threshold_uncertainty_score":0.008346558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03667172079970912,"score_gpt":0.2561642343591773,"score_spread":0.2194925135594682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}