{"id":"W2416923936","doi":"10.1139/w11-135","title":"Cangene Gold Medal Award Lecture — Genomic analysis and modification of<i>Burkholderia cepacia</i>complex bacteriophages<sup>1</sup>This article is based on a presentation by Dr. Karlene Lynch at the 61st Annual Meeting of the Canadian Society of Microbiologists in St. John’s, Newfoundland and Labrador, on 21 June 2011. Dr. Lynch was the recipient of the 2011 Cangene Gold Medal as the Canadian Graduate Student Microbiologist of the Year, an annual award sponsored by Cangene Corporation intended to recognize excellence in graduate research.","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates; Killam Trusts; Cystic Fibrosis Canada","keywords":"Phage therapy; Bacteriophage; Lytic cycle; Microbiology; Biology; Burkholderia; Burkholderia cepacia complex; Virulence; Pseudomonas aeruginosa; Staphylococcus aureus; Antibiotic resistance; Phage typing; Genome; Bacteria; Virology; Gene; Genetics; Antibiotics; Serotype; Virus; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002418904,0.0009389024,0.0004810067,0.000700106,0.0008197348,0.00136131,0.0009817474,0.001785256,0.01483994],"category_scores_gemma":[0.001001925,0.0003651165,0.0006567436,0.0002335726,0.0006578906,0.0006155332,0.001239859,0.00208901,0.005368982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002514911,"about_ca_system_score_gemma":0.002315314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003165001,"about_ca_topic_score_gemma":0.007770023,"domain_scores_codex":[0.9988075,0.0001258802,0.00003267225,0.0001694239,0.0005829529,0.0002816284],"domain_scores_gemma":[0.9984079,0.00007257207,0.00004068821,0.00005079758,0.0004484981,0.0009795618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001691181,0.0006137756,0.003177394,0.00027626,0.0000833551,0.0009344436,0.0003170774,0.0005212601,0.3380952,0.002864889,0.5264185,0.1250066],"study_design_scores_gemma":[0.0002440336,0.003369608,0.01055771,0.00007507789,0.000100325,0.001440387,0.0003459577,0.001254585,0.1905403,0.0009251314,0.7910584,0.00008847931],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.3275335,0.06746854,0.04627958,0.1466158,0.2358477,0.002402576,0.004316295,0.002909971,0.1666259],"genre_scores_gemma":[0.2954377,0.02446451,0.02323924,0.01497089,0.01448302,0.0003948669,0.005579262,0.0008014404,0.6206291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01483994,"threshold_uncertainty_score":0.04964459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04267923100770192,"score_gpt":0.2860308979883575,"score_spread":0.2433516669806555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}