{"id":"W2416944827","doi":"10.1038/srep14724","title":"Inhibition of HIV-1 assembly by coiled-coil domain containing protein 8 in human cells","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"State Key Laboratory of Infectious Disease Prevention and Control; Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Coiled coil; Human immunodeficiency virus (HIV); Domain (mathematical analysis); Protein structure; Protein domain; Computational biology; Cell biology; Bioinformatics; Chemistry; Biology; Virology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001577797,0.0002277897,0.0002466154,0.0001583229,0.0001754671,0.0002496599,0.0001376549,0.0001742515,0.000862132],"category_scores_gemma":[0.00008079703,0.00008828397,0.0001592084,0.000140775,0.0001164073,0.00007234846,0.0001320459,0.0003182595,0.0003588297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002681981,"about_ca_system_score_gemma":0.0002203955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008818972,"about_ca_topic_score_gemma":0.001140293,"domain_scores_codex":[0.9998786,0.00003131183,0.00001252548,0.00001788336,0.00003257797,0.00002710735],"domain_scores_gemma":[0.9999661,0.000009215417,0.000005135872,0.000007648217,0.000005390501,0.000006461541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003178449,0.0001438634,0.0003132309,0.00008432884,0.00001036471,0.00006511831,0.00003343224,0.000172203,0.9912233,0.0002107997,0.0004579441,0.006967548],"study_design_scores_gemma":[0.00005285211,0.000697588,0.002329636,0.00000775432,0.00001560568,0.0001718712,0.0000165366,0.00114353,0.9847285,0.00004422015,0.01078853,0.000003275176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983291,0.009138484,0.002183582,0.0002364639,0.00008496739,0.00008383857,0.0005125137,0.0001446059,0.004324492],"genre_scores_gemma":[0.9875173,0.004468156,0.002914119,0.0001178341,0.00001981177,0.0001167915,0.0009006296,0.00001177427,0.003933646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008818972,"threshold_uncertainty_score":0.00288409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01925906955393527,"score_gpt":0.2682979259831481,"score_spread":0.2490388564292128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}