{"id":"W2417346077","doi":"10.1016/j.niox.2015.02.023","title":"Hydrogen sulfide maintains mitochondrial DNA replication via demethylation of TFAM","year":2015,"lang":"en","type":"article","venue":"Nitric Oxide","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lakehead University","funders":"","keywords":"TFAM; DNA demethylation; Mitochondrial DNA; Chemistry; Demethylation; Hydrogen sulfide; Biochemistry; Gene; Sulfur; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003787601,0.0001318049,0.0001652739,0.00009123277,0.00003220584,0.000006111006,0.0002514716,0.0002330099,0.000008250527],"category_scores_gemma":[0.0008630375,0.0001325455,0.00008269262,0.0002108831,0.00008260642,0.000004624307,0.0001127588,0.00007613655,0.00002754503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005227725,"about_ca_system_score_gemma":0.0001259656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008320795,"about_ca_topic_score_gemma":0.00001595266,"domain_scores_codex":[0.9987553,0.0001363581,0.0003298282,0.0003972663,0.0001561043,0.0002251284],"domain_scores_gemma":[0.9987179,0.00003810117,0.00019573,0.0007391853,0.0002016003,0.0001074497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001475559,0.00004604302,0.007641086,0.000004127779,0.00003853,0.000001090293,0.00001736361,0.00007844263,0.9881081,0.0001476713,0.001860985,0.001908989],"study_design_scores_gemma":[0.0008264852,0.0001881924,0.005013966,0.000003276274,0.00002788768,0.00002735761,0.00003225058,0.0001602306,0.958352,0.002152744,0.03304765,0.0001680133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827827,0.0005680558,0.01489299,0.00008358397,0.0001883486,0.0002181406,0.000009496751,0.00002255594,0.001234189],"genre_scores_gemma":[0.9905138,0.00003018058,0.008233391,0.0001382641,0.0004379536,0.00002886373,0.0002478191,0.00002104095,0.0003487139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03118667,"threshold_uncertainty_score":0.5405047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02252340427249274,"score_gpt":0.2722069573601794,"score_spread":0.2496835530876867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}