{"id":"W2417498474","doi":"10.1038/srep14971","title":"Metabolic changes of H2S in smokers and patients of COPD which might involve in inflammation, oxidative stress and steroid sensitivity","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakehead University","funders":"National Natural Science Foundation of China","keywords":"COPD; Oxidative stress; Inflammation; Pathogenesis; Medicine; Internal medicine; Cystathionine beta synthase; Endocrinology; Dexamethasone; Glutathione; Superoxide dismutase; Systemic inflammation; Tumor necrosis factor alpha; Immunology; Chemistry; Enzyme; Biochemistry; Cysteine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001402426,0.0001682271,0.0004258442,0.0003999378,0.0002650159,0.0002877171,0.00008774206,0.0003485406,0.001337062],"category_scores_gemma":[0.0003758499,0.0001149772,0.0002462195,0.000389755,0.0001434149,0.0001878621,0.0001486036,0.0002629915,0.0001802346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001355306,"about_ca_system_score_gemma":0.0001469337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007654608,"about_ca_topic_score_gemma":0.001060147,"domain_scores_codex":[0.9998951,0.00002471684,0.00001477807,0.00002463251,0.00002060397,0.00002012948],"domain_scores_gemma":[0.9998566,0.00001719233,0.00004293047,0.000008092525,0.00001864794,0.00005662706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004187832,0.0003221014,0.9526451,0.0001106133,0.0001601652,0.001145329,0.000491104,0.0000350747,0.02904765,0.00005041272,0.0001783495,0.01162637],"study_design_scores_gemma":[0.00001943626,0.0007840222,0.9961388,0.000006743808,0.00005540984,0.0009990431,0.0002906376,0.00005855561,0.00121659,0.00005359505,0.0003722907,0.000005005631],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977947,0.001581336,0.0000563086,0.0000428261,0.00001067658,0.000006251877,0.0001076207,0.000003161509,0.0003970689],"genre_scores_gemma":[0.9989427,0.0004617271,0.00006323553,0.00004016417,0.00001351079,0.000008122905,0.0001406522,0.000001116766,0.0003288935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001337062,"threshold_uncertainty_score":0.004472911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01553612372108477,"score_gpt":0.2452700162847111,"score_spread":0.2297338925636263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}