{"id":"W2417498474","doi":"10.1038/srep14971","title":"Metabolic changes of H2S in smokers and patients of COPD which might involve in inflammation, oxidative stress and steroid sensitivity","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakehead University","funders":"National Natural Science Foundation of China","keywords":"COPD; Oxidative stress; Inflammation; Pathogenesis; Medicine; Internal medicine; Cystathionine beta synthase; Endocrinology; Dexamethasone; Glutathione; Superoxide dismutase; Systemic inflammation; Tumor necrosis factor alpha; Immunology; Chemistry; Enzyme; Biochemistry; Cysteine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001077823,0.00009590911,0.000213289,0.0001617908,0.00001855511,0.00001418704,0.0000445674,0.00009947728,9.692041e-7],"category_scores_gemma":[0.0005057578,0.00008877628,0.00001274551,0.0002460644,0.0003245182,0.00000993659,0.0001547085,0.00004775137,1.054926e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001070106,"about_ca_system_score_gemma":0.00008281007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001300547,"about_ca_topic_score_gemma":0.004981426,"domain_scores_codex":[0.9988132,0.0001557157,0.0003341303,0.0004082856,0.0001516725,0.000137061],"domain_scores_gemma":[0.9989644,0.00002144043,0.0002924934,0.0003108898,0.0003581319,0.00005260288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002956979,0.00004767388,0.6558039,0.00002603734,0.00001252714,0.000007677984,0.0007610952,0.00001646049,0.342606,0.000008747275,0.00007350599,0.0006068121],"study_design_scores_gemma":[0.0004241103,0.00008418303,0.2255799,0.00003579919,0.000006586546,0.00001193143,0.0003472983,0.00002906088,0.7721919,0.0002950362,0.0009008038,0.00009342007],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985156,0.0006146852,0.000009549894,0.00003697561,0.0004956521,0.0002080609,0.00001321864,0.00000202559,0.0001042514],"genre_scores_gemma":[0.9995653,0.00003289842,0.0001938083,0.000006646957,0.00001598207,0.000007651568,0.0001394888,0.000005216058,0.00003299359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.430224,"threshold_uncertainty_score":0.3620192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01553612372108477,"score_gpt":0.2452700162847111,"score_spread":0.2297338925636263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}