{"id":"W2417506336","doi":"10.1038/srep16300","title":"Risperidone and NAP protect cognition and normalize gene expression in a schizophrenia mouse model","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Tel Aviv University; Ministry of Science, Technology and Space; Canadian Friends of Tel Aviv University","keywords":"Nap; Risperidone; Neuroprotection; DISC1; Schizophrenia (object-oriented programming); Pharmacology; Neuroscience; Medicine; Biology; Psychiatry; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004572881,0.00008284888,0.00007657932,0.00006254371,0.00009051422,0.00007771788,0.00002132037,0.00007886507,0.000002616747],"category_scores_gemma":[0.00007069646,0.00007138643,0.00001559095,0.00007179944,0.0001109366,0.00001483135,0.00007034695,0.00004217261,8.908351e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008526171,"about_ca_system_score_gemma":0.00006506976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007189536,"about_ca_topic_score_gemma":0.00002655635,"domain_scores_codex":[0.9991419,0.00002784737,0.0001807839,0.0003983792,0.0001392077,0.000111827],"domain_scores_gemma":[0.9995152,0.000001413931,0.00008650441,0.0002169859,0.00008171326,0.00009821521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001273289,0.00002472398,0.0008370075,0.000008514924,0.00000284175,0.000009190782,0.0001092802,0.0003965175,0.9970633,0.00000148492,0.0008575781,0.0005622603],"study_design_scores_gemma":[0.0006218294,0.00004247725,0.0004724665,0.00001807912,0.000004996883,0.0001275556,0.00003646822,0.003219936,0.9931077,0.0007010681,0.001534962,0.0001125084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966834,0.0004140575,0.002076083,0.00003196237,0.0003898744,0.0002359779,0.000002878304,0.00001153046,0.0001542979],"genre_scores_gemma":[0.9960888,0.00002187326,0.002126443,0.00002161779,0.00003464807,0.00002948173,0.0001200773,0.000007702033,0.001549332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003955618,"threshold_uncertainty_score":0.2911054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01596806760979278,"score_gpt":0.2367679571126489,"score_spread":0.2207998895028561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}