{"id":"W2417583025","doi":"10.1093/neuonc/now101","title":"Pediatric high-grade glioma: biologically and clinically in need of new thinking","year":2016,"lang":"en","type":"review","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":364,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; SickKids Foundation; Hospital for Sick Children","funders":"University of California, San Francisco; Cancer Research UK; Brain Tumour Charity; Rosetrees Trust; Deutsches Krebsforschungszentrum; National Brain Tumor Society","keywords":"Clinical trial; Glioma; Pace; Disease; Perspective (graphical); Bioinformatics; Medicine; Neuroscience; Biology; Internal medicine; Cancer research; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004880036,0.0004822509,0.003585086,0.0006406057,0.00003327372,0.00001038175,0.000257858,0.00105227,0.00009970734],"category_scores_gemma":[0.0009941852,0.0002808675,0.0004537217,0.0005652955,0.0001394378,0.00003114887,0.0002561868,0.0005971906,0.00005644638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001887665,"about_ca_system_score_gemma":0.0009940033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004882546,"about_ca_topic_score_gemma":0.00001361336,"domain_scores_codex":[0.9965127,0.0004919006,0.001573506,0.0007554808,0.0002253782,0.0004410209],"domain_scores_gemma":[0.9947463,0.003526471,0.0009100913,0.0004554724,0.00006091022,0.0003008072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009024591,0.000892073,0.005935461,0.002329282,0.0001565862,0.002511309,0.00004662829,5.603617e-8,0.0002658635,0.0004537708,0.001862444,0.9854563],"study_design_scores_gemma":[0.006046924,0.00469273,0.001776198,0.002389849,0.002014019,0.0007068789,0.000007426586,3.132656e-7,0.00002080479,0.0006056662,0.9814439,0.0002952669],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01871586,0.9773964,0.000003319133,0.00144514,0.0006074116,0.001342613,0.00002713883,0.00005303568,0.0004090774],"genre_scores_gemma":[0.00208646,0.9958907,0.0007231888,0.0004051646,0.0006929936,0.0001017128,0.00003614359,0.00005186599,0.00001182225],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.985161,"threshold_uncertainty_score":0.9999644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06719057590261662,"score_gpt":0.3775193674760006,"score_spread":0.310328791573384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}