{"id":"W2417724913","doi":"10.1371/journal.pone.0156739","title":"Nonhuman Primate IFITM Proteins Are Potent Inhibitors of HIV and SIV","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Primate; Nonhuman primate; Virology; Infectivity; Non human primate; Simian immunodeficiency virus; Virus; Macaca nemestrina; Viral replication; Macaque; Lentivirus; Viral disease; Neuroscience; Evolutionary biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009895594,0.0001121765,0.0002554545,0.00008029091,0.00006395145,0.000004873595,0.00009846545,0.0001179857,0.0003378812],"category_scores_gemma":[0.0001057279,0.00007352586,0.00004067963,0.00003209821,0.0002144882,0.00005818947,0.00009249004,0.00009201298,0.0003468698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002111251,"about_ca_system_score_gemma":0.0000210285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008911466,"about_ca_topic_score_gemma":0.000003830507,"domain_scores_codex":[0.9992793,0.00009947937,0.000218102,0.0001651354,0.00003363656,0.0002044076],"domain_scores_gemma":[0.9995262,0.00005886204,0.0001228893,0.0002035844,0.00007342323,0.00001505605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003444828,0.0005324385,0.002544507,0.00006353811,0.0002115925,0.000001930552,0.0001967395,7.964174e-9,0.9942723,0.0003082841,0.0004062396,0.001117952],"study_design_scores_gemma":[0.0009419179,0.0003367226,0.009416198,0.0005541705,0.0000419158,0.000007351889,0.00008582479,2.038435e-7,0.987429,0.00005657248,0.001022824,0.000107254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996824,0.001236222,0.00002212553,0.0008450734,0.0000591155,0.0002773191,0.00003987641,0.00004031256,0.0006559343],"genre_scores_gemma":[0.991854,0.0001489757,0.00009123371,0.00004792298,0.00001690439,0.00002338245,0.000006130991,0.0000134347,0.007797995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007142061,"threshold_uncertainty_score":0.4458426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02345268077769646,"score_gpt":0.2127543729227199,"score_spread":0.1893016921450234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}