{"id":"W2417787511","doi":"10.1038/bcj.2016.36","title":"Transcriptome analysis of G protein-coupled receptors in distinct genetic subgroups of acute myeloid leukemia: identification of potential disease-specific targets","year":2016,"lang":"en","type":"article","venue":"Blood Cancer Journal","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Fonds de Recherche du Québec - Santé; Deutsche Krebshilfe; Université de Montréal; Government of Canada; Génome Québec; Compute Canada; Genome Canada","keywords":"Chemokine receptor; CX3CR1; Myeloid leukemia; Receptor; G protein-coupled receptor; Biology; CXCR4; Leukemia; Immunology; Myeloid; Cancer research; Chemokine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008660281,0.00009951096,0.000294235,0.0004541769,0.0002192777,0.000329923,0.00007035598,0.0001724681,0.000886357],"category_scores_gemma":[0.000178784,0.00008608837,0.0002530309,0.0005356529,0.0001127462,0.0001273184,0.000220184,0.0001949861,0.0002772633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001504404,"about_ca_system_score_gemma":0.0001925886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007073699,"about_ca_topic_score_gemma":0.0009877943,"domain_scores_codex":[0.9998646,0.00001395972,0.00001005529,0.0000426951,0.00003147437,0.0000372898],"domain_scores_gemma":[0.9999473,0.00001006096,0.00001698237,0.000005099756,0.00001071888,0.000009916087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004641227,0.00002886269,0.05292646,0.0001271613,0.00004885692,0.0001701038,0.0001962738,0.0002416574,0.933795,0.0001120251,0.0003032211,0.01158631],"study_design_scores_gemma":[0.00001561327,0.0002341996,0.9465328,0.00001800988,0.0001382925,0.001027567,0.0005757698,0.002315373,0.04431569,0.0002260101,0.004586982,0.00001371704],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957022,0.0008207287,0.0008484147,0.00004364568,0.000005357369,0.00001333525,0.002005165,0.00001964181,0.0005415009],"genre_scores_gemma":[0.992586,0.0008208427,0.001399555,0.00007441997,0.0000101644,0.00004505345,0.004320693,0.00001648737,0.0007269074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000886357,"threshold_uncertainty_score":0.002965152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01087940075883715,"score_gpt":0.2460129510290285,"score_spread":0.2351335502701914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}