{"id":"W2417787511","doi":"10.1038/bcj.2016.36","title":"Transcriptome analysis of G protein-coupled receptors in distinct genetic subgroups of acute myeloid leukemia: identification of potential disease-specific targets","year":2016,"lang":"en","type":"article","venue":"Blood Cancer Journal","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Fonds de Recherche du Québec - Santé; Deutsche Krebshilfe; Université de Montréal; Government of Canada; Génome Québec; Compute Canada; Genome Canada","keywords":"Chemokine receptor; CX3CR1; Myeloid leukemia; Receptor; G protein-coupled receptor; Biology; CXCR4; Leukemia; Immunology; Myeloid; Cancer research; Chemokine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000396126,0.0001752025,0.0007403187,0.0005923909,0.00003811445,0.000009881937,0.0001693942,0.00008653945,0.0009048205],"category_scores_gemma":[0.00003386148,0.000124814,0.0004975975,0.000864278,0.0001240837,0.00009719055,0.00001648934,0.0001836133,6.170847e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001992174,"about_ca_system_score_gemma":0.0003367458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008716402,"about_ca_topic_score_gemma":0.00002397146,"domain_scores_codex":[0.9975923,0.00006890226,0.001239917,0.0002540362,0.0005971542,0.0002476701],"domain_scores_gemma":[0.9983735,0.00002546883,0.0007998993,0.0002518775,0.0003587187,0.0001904987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007458032,0.0002543056,0.120543,0.0001224879,0.001764348,0.00002703961,0.0002140224,0.0001720731,0.8719826,0.000006733276,0.0000264006,0.004141273],"study_design_scores_gemma":[0.004097546,0.0001730159,0.408108,0.0006111666,0.005805746,0.00002305855,0.0000572262,0.0004981423,0.5803185,0.00006244847,0.00007889616,0.0001662381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897439,0.00511645,0.004298659,0.0002122624,0.0002133359,0.0002898134,0.0001124564,0.000006970789,0.000006106012],"genre_scores_gemma":[0.996366,0.002949778,0.0002830898,0.000004550286,0.0002186752,0.00002289239,0.00001828713,0.00002421362,0.0001125143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2916641,"threshold_uncertainty_score":0.990715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01087940075883715,"score_gpt":0.2460129510290285,"score_spread":0.2351335502701914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}