{"id":"W2417863514","doi":"10.1080/15384101.2016.1191248","title":"Global chromatin architecture defines functional cancer hierarchies","year":2016,"lang":"en","type":"editorial","venue":"Cell Cycle","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Biology; Chromatin; Histone; Computational biology; Identification (biology); Cancer; Genetics; Cancer research; Evolutionary biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003324543,0.001976597,0.001996501,0.001277903,0.001333807,0.004430329,0.001939901,0.007195171,0.004114141],"category_scores_gemma":[0.007949162,0.0009645094,0.001144188,0.0006201161,0.00502512,0.005138095,0.002242375,0.02057422,0.00230906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001606133,"about_ca_system_score_gemma":0.001159078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007709743,"about_ca_topic_score_gemma":0.001947143,"domain_scores_codex":[0.9987295,0.0002230549,0.0001798785,0.0002852488,0.0004521463,0.000130071],"domain_scores_gemma":[0.9937093,0.004237818,0.0003094712,0.0001846032,0.001094994,0.000463843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001624255,0.00001449144,0.0001745345,0.0009992406,0.00007308317,0.0003088002,0.0001542431,0.0001799272,0.001340632,0.007900675,0.9519027,0.03678933],"study_design_scores_gemma":[0.00007208865,0.00006229995,0.0006670409,0.0004429627,0.00006540271,0.0004016662,0.0001027759,0.0002077313,0.0005520781,0.01101216,0.9863704,0.0000434457],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.0004692693,0.0891608,0.001167417,0.1546568,0.7522103,0.00001998118,0.0001929194,0.0001526373,0.001969923],"genre_scores_gemma":[0.003434151,0.0643714,0.0004359528,0.06491839,0.8601205,0.00003005519,0.00009706868,0.00005326585,0.006539283],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.007195171,"threshold_uncertainty_score":0.01758206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006749429459332292,"score_gpt":0.2611621989564258,"score_spread":0.2544127694970936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}