{"id":"W2417869376","doi":"10.1002/adfm.201602036","title":"A Universal Platform for Macromolecular Deliveryinto Cells Using Gold Nanoparticle Layers via the Photoporation Effect","year":2016,"lang":"en","type":"article","venue":"Advanced Functional Materials","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"College of Family Physicians of Canada; University of Toronto","funders":"","keywords":"Photothermal therapy; Transfection; Materials science; Lipofectamine; Endocytosis; Colloidal gold; Intracellular; Biophysics; Nanotechnology; Viability assay; Cytotoxicity; Nanoparticle; Cytosol; Cell culture; Cell; Cell biology; In vitro; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001697189,0.0001409417,0.0001170558,0.00002192918,0.0001080725,0.00002738335,0.0001069808,0.00007903888,0.00008028874],"category_scores_gemma":[0.00003363959,0.0000877344,0.00007767664,0.0000397472,0.00005699122,0.00002453084,0.00004975652,0.00001794223,0.00003098048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003764731,"about_ca_system_score_gemma":0.00003529928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002428541,"about_ca_topic_score_gemma":0.00000838899,"domain_scores_codex":[0.9992152,0.0000419583,0.0001724391,0.0002646757,0.0001000597,0.0002056237],"domain_scores_gemma":[0.9995157,0.00004046259,0.00009313918,0.0002019615,0.0001092967,0.00003943713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001104883,0.00001408579,0.00001776613,0.000009234333,0.00004857278,0.000001415468,0.00000813017,0.0003912667,0.9964256,0.00005610274,0.0004948151,0.001428152],"study_design_scores_gemma":[0.0009212331,0.0005247091,0.00005564593,0.00001798436,0.00003042423,0.00001138849,0.00001719212,0.00006047039,0.9946668,0.0002383577,0.003314451,0.0001413217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9614146,0.0000535972,0.0373398,0.00007543027,0.0006391657,0.0003640588,0.00007863624,0.00001280714,0.00002185432],"genre_scores_gemma":[0.9984304,0.00002222748,0.0004655704,0.000267154,0.0002059253,0.00006156942,0.00006749255,0.00001940749,0.0004602694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03701574,"threshold_uncertainty_score":0.3577705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01194254988528044,"score_gpt":0.2323159277232737,"score_spread":0.2203733778379933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}